{"id":"W2033857478","doi":"10.1016/j.jconrel.2011.09.098","title":"The journey of a drug-carrier in the body: An anatomo-physiological perspective","year":2011,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":694,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"Centers for Disease Control and Prevention; Canada Research Chairs; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Biodistribution; Drug delivery; Nanotechnology; Perspective (graphical); Drug carrier; Engineering ethics; Medicine; Risk analysis (engineering); Management science; Computer science; Engineering; Materials science; Biology; Biotechnology; Artificial intelligence","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006048397,0.0004167012,0.002800863,0.0002653369,0.0001946565,0.0001371587,0.001727721,0.0002136884,0.0001647657],"category_scores_gemma":[0.002184079,0.0001668056,0.001326844,0.0004182396,0.000414559,0.0002830154,0.00008346004,0.001120226,0.00003163376],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002231818,"about_ca_system_score_gemma":0.001264678,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005672086,"about_ca_topic_score_gemma":0.00002155332,"domain_scores_codex":[0.9920897,0.004330642,0.002080533,0.0002950888,0.0007341595,0.0004698065],"domain_scores_gemma":[0.9932053,0.001987454,0.003122398,0.0006920233,0.0007584732,0.0002343654],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.07577585,0.01954345,0.00006562452,0.008795611,0.007324952,0.01138742,0.02975576,0.000548685,0.03287613,0.1191645,0.04183555,0.6529265],"study_design_scores_gemma":[0.05057312,0.006381153,0.000155153,0.01800596,0.01224769,0.002642349,0.01595675,0.000469441,0.001262684,0.01733755,0.8725562,0.002411922],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03219071,0.965757,0.000007760403,0.0002427002,0.0005191513,0.00099466,0.00002944586,0.000008375649,0.0002502343],"genre_scores_gemma":[0.09094235,0.9082543,0.00004650266,0.0001197225,0.0004832826,0.00004994004,8.139698e-7,0.00003175099,0.00007133542],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8307207,"threshold_uncertainty_score":0.6802134,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03447074710322676,"score_gpt":0.3193328968079268,"score_spread":0.2848621497047,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}