{"id":"W2033891772","doi":"10.1089/ars.2009.2569","title":"Evidence Supporting a Role for Endoplasmic Reticulum Stress in the Development of Atherosclerosis in a Hyperglycaemic Mouse Model","year":2009,"lang":"en","type":"article","venue":"Antioxidants and Redox Signaling","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; McMaster University Medical Centre","funders":"Canadian Institutes of Health Research","keywords":"Endoplasmic reticulum; Endocrinology; Internal medicine; Unfolded protein response; Medicine; Endothelium; Apolipoprotein B; Oxidative stress; Apolipoprotein E; Endothelial dysfunction; Diabetes mellitus; Intracellular; Glucosamine; Biology; Cholesterol; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003976526,0.0001399357,0.0001801647,0.0000574874,0.00007241152,0.00002478426,0.0001634397,0.00008205658,0.000001318843],"category_scores_gemma":[0.0001124143,0.0001047937,0.00006161407,0.00008047709,0.0000444879,0.00001105888,0.00003462513,0.00007093918,1.568163e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007051454,"about_ca_system_score_gemma":0.00008464083,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000166771,"about_ca_topic_score_gemma":0.00006720858,"domain_scores_codex":[0.9988381,0.00004245239,0.000423177,0.0002959225,0.0001273506,0.0002729935],"domain_scores_gemma":[0.9995747,0.00004321493,0.0001338341,0.0001654878,0.00003888461,0.0000438647],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009021931,0.0001145282,0.01706349,0.00005273907,0.000007910507,0.000001214301,0.0009357954,0.002009303,0.9780028,0.0000517768,0.000005696298,0.001664542],"study_design_scores_gemma":[0.0007969325,0.0001288411,0.005722419,0.0004482055,0.00001527695,0.000003318634,0.001428773,0.008718407,0.9823812,0.0001675516,0.00001094962,0.0001781829],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975314,0.0009574547,0.001061851,0.00006114601,0.00001178769,0.0002976719,0.00001905777,0.000004028351,0.00005562118],"genre_scores_gemma":[0.9965932,0.0003954823,0.002814232,0.00008597653,0.00002181136,0.00003428426,0.00001513991,0.00001010361,0.00002976147],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01134107,"threshold_uncertainty_score":0.4273361,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02259559355097923,"score_gpt":0.2763971882624511,"score_spread":0.2538015947114719,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}