{"id":"W2033905999","doi":"10.1016/j.tibs.2007.09.012","title":"14-3-3 Cruciform-binding proteins as regulators of eukaryotic DNA replication","year":2007,"lang":"en","type":"review","venue":"Trends in Biochemical Sciences","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Cruciform; Eukaryotic DNA replication; Cell biology; DNA replication; Replication (statistics); Biology; Origin recognition complex; Computational biology; Control of chromosome duplication; Genetics; DNA; Virology; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"not_applicable","genre":"review","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"},{"model":"gpt","categories":[],"domain":null,"study_design":"design_other","genre":"review","about_ca_system":false,"about_ca_topic":false,"confidence":"high","status":"direct model label, unvalidated"}],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009087377,0.001158761,0.001768021,0.001455329,0.0003835463,0.001304729,0.001455075,0.001341677,0.001796324],"category_scores_gemma":[0.0005401791,0.0004346347,0.0003736325,0.002063592,0.0007850713,0.001304976,0.0007119407,0.002002812,0.00220416],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001102744,"about_ca_system_score_gemma":0.001165231,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00111573,"about_ca_topic_score_gemma":0.002350801,"domain_scores_codex":[0.9997842,0.00002814695,0.00002565956,0.0000403568,0.00009450647,0.00002722186],"domain_scores_gemma":[0.9997751,0.00006773142,0.00004123482,0.000008374598,0.00007418679,0.00003340718],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.000211388,0.00005785181,0.0002784599,0.005785998,0.0001029833,0.0003704622,0.00005853072,0.0008042371,0.007680473,0.006945055,0.03172617,0.9459784],"study_design_scores_gemma":[0.00003232109,0.00004794008,0.0005162099,0.0006391925,0.00008346821,0.0007359453,0.00004102124,0.0001570333,0.001727139,0.001919558,0.9940837,0.00001645558],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002258926,0.9979171,0.0004080758,0.0002454652,0.0003412858,0.00000522697,0.00001263034,0.00001391277,0.0008304851],"genre_scores_gemma":[0.001430184,0.9965462,0.0004857577,0.0002417409,0.0002471971,0.000008956622,0.00004777674,0.000002300595,0.0009899396],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001796324,"threshold_uncertainty_score":0.008001029,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07170719045834975,"score_gpt":0.4112563198552027,"score_spread":0.3395491293968529,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}