{"id":"W2033905999","doi":"10.1016/j.tibs.2007.09.012","title":"14-3-3 Cruciform-binding proteins as regulators of eukaryotic DNA replication","year":2007,"lang":"en","type":"review","venue":"Trends in Biochemical Sciences","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Cruciform; Eukaryotic DNA replication; Cell biology; DNA replication; Replication (statistics); Biology; Origin recognition complex; Computational biology; Control of chromosome duplication; Genetics; DNA; Virology; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"not_applicable","genre":"review","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"},{"model":"gpt","categories":[],"domain":null,"study_design":"design_other","genre":"review","about_ca_system":false,"about_ca_topic":false,"confidence":"high","status":"direct model label, unvalidated"}],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009310087,0.0003678509,0.0006928737,0.0005801195,0.0001009571,0.00003594069,0.0009029757,0.0006035074,0.0001122566],"category_scores_gemma":[0.0005502143,0.0003005767,0.0003783292,0.00158183,0.000633728,0.0000124298,0.0002649316,0.0003128784,0.00002826878],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001132252,"about_ca_system_score_gemma":0.0002323493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005299048,"about_ca_topic_score_gemma":0.00001779777,"domain_scores_codex":[0.9970805,0.00008853486,0.0008831693,0.001076621,0.0004091132,0.0004620858],"domain_scores_gemma":[0.9983155,0.00005654595,0.0005848705,0.000852843,0.00007048595,0.0001197278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002121085,0.0001820474,0.0001044112,0.001126647,0.00006388133,0.000003162573,0.00002697481,0.000001304399,0.05263824,0.0003511107,0.001552995,0.943928],"study_design_scores_gemma":[0.0001965372,0.0003991786,0.00006500333,0.004006003,0.0001123516,0.0001006839,0.00003282418,0.000004114756,0.2657434,0.0001750249,0.7284973,0.0006675891],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02650834,0.9623723,0.0000432626,0.00006117984,0.0002753201,0.0006673133,0.00004687335,0.00003046403,0.009994921],"genre_scores_gemma":[0.01728758,0.975212,0.003077305,0.00003464209,0.0003858551,0.0002943373,0.0005382359,0.00005971481,0.003110337],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9432604,"threshold_uncertainty_score":0.9999446,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07170719045834975,"score_gpt":0.4112563198552027,"score_spread":0.3395491293968529,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}