{"id":"W2033918255","doi":"10.1016/j.neuint.2012.10.006","title":"Both acute and subchronic treatments with pindolol, a 5-HT1A and β1 and β2 adrenoceptor antagonist, elevate regional serotonin synthesis in the rat brain: An autoradiographic study","year":2012,"lang":"en","type":"article","venue":"Neurochemistry International","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University","funders":"Canadian Institutes of Health Research; Ministerul Cercetării, Inovării şi Digitalizării","keywords":"Pindolol; Antagonist; Serotonin; 5-HT1A receptor; Pharmacology; Endocrinology; 5-HT receptor; Medicine; Internal medicine; Chemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001260632,0.0006932413,0.000638146,0.0006573144,0.000373398,0.0004100347,0.0003564644,0.0004667075,0.003951667],"category_scores_gemma":[0.0001303169,0.0004424344,0.0005212083,0.0004684268,0.0007640633,0.0004669451,0.00024123,0.001404927,0.000722268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005115163,"about_ca_system_score_gemma":0.0003587017,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004222998,"about_ca_topic_score_gemma":0.01354232,"domain_scores_codex":[0.9998666,0.00001098572,0.000007115593,0.00002152384,0.00002458015,0.00006913842],"domain_scores_gemma":[0.9997972,0.00006546644,0.00003323856,0.00002960178,0.00001776811,0.00005682141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007314867,0.0001050029,0.0001711288,0.00005911391,0.00001483809,0.0001168923,0.00004847188,0.00002768247,0.997179,0.00007562155,0.00004932436,0.001421354],"study_design_scores_gemma":[0.0000470528,0.003035346,0.008907526,0.000009163145,0.00006570698,0.0002759571,0.0001186184,0.0001378148,0.9864869,0.00004705504,0.0008583678,0.00001052186],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895397,0.004245028,0.001882227,0.0001432567,0.00006630946,0.00004889978,0.0006460665,0.0001167891,0.00331179],"genre_scores_gemma":[0.98128,0.004726502,0.001781384,0.0001140842,0.00004531262,0.0001045306,0.001185423,0.00004918296,0.01071375],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004222998,"threshold_uncertainty_score":0.01321965,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03063279567438429,"score_gpt":0.2987767088253302,"score_spread":0.2681439131509459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}