{"id":"W2033950365","doi":"10.1021/bi801751s","title":"Adhesion-Induced Unclasping of Cytoplasmic Tails of Integrin α<sub>IIb</sub>β<sub>3</sub><sup>,</sup>","year":2008,"lang":"en","type":"article","venue":"Biochemistry","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Heart, Lung, and Blood Institute","keywords":"Integrin; Cytoplasm; Platelet; Chemistry; Transmembrane protein; RGD motif; Adhesion; Cell adhesion; Fibrin; Cell biology; Intracellular; Binding site; Biophysics; Molecular biology; Biochemistry; Biology; Cell; Receptor; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006872839,0.0002191236,0.0001079596,0.00008185764,0.0001303157,0.0002352244,0.0001372558,0.0002142584,0.001474999],"category_scores_gemma":[0.0001126725,0.0001061749,0.0002656593,0.00009895211,0.0001644361,0.0001719489,0.0002242745,0.0004313156,0.0004077418],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002189403,"about_ca_system_score_gemma":0.0001229746,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000422253,"about_ca_topic_score_gemma":0.0009171343,"domain_scores_codex":[0.9999286,0.00001076256,0.000003397414,0.000015723,0.00001699954,0.00002444499],"domain_scores_gemma":[0.9999359,0.00001437584,0.00002575076,0.000007239987,0.000005577459,0.00001118561],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000781456,0.000009270311,0.0001767066,0.00002776203,0.000004741554,0.00009501466,0.00001616415,0.00001404633,0.9987154,0.00008017658,0.0000532679,0.0007294182],"study_design_scores_gemma":[0.00001841434,0.000207898,0.02836117,0.00001128283,0.00002032385,0.0008341563,0.0000762898,0.0006982573,0.9660137,0.00007115726,0.003680949,0.000006396487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948183,0.001707919,0.001669892,0.00005331595,0.00002271577,0.00001488859,0.0001560437,0.00001450343,0.001542428],"genre_scores_gemma":[0.994412,0.000740246,0.001137243,0.0001359399,0.00001410785,0.00002630711,0.0005293249,0.00001072237,0.002994073],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001474999,"threshold_uncertainty_score":0.004934371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01753850748665637,"score_gpt":0.2380116566713221,"score_spread":0.2204731491846658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}