{"id":"W2034012805","doi":"10.1021/bi800925e","title":"Distortion-Dependent Unhooking of Interstrand Cross-Links in Mammalian Cell Extracts","year":2008,"lang":"en","type":"article","venue":"Biochemistry","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"National Cancer Institute","keywords":"Distortion (music); Chemistry; Cell; Biophysics; Physics; Biology; Biochemistry; Optoelectronics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007988028,0.0001361545,0.000123599,0.00002811238,0.0000301204,0.000007077791,0.0001575408,0.0002523039,0.00002615856],"category_scores_gemma":[0.00003047773,0.0001513631,0.00007705609,0.00005473124,0.00007969374,0.000002433472,0.00005566527,0.000147846,0.000002418293],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002210253,"about_ca_system_score_gemma":0.00005597074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002340583,"about_ca_topic_score_gemma":0.00001002766,"domain_scores_codex":[0.9991436,0.000007539263,0.0002667947,0.0002719426,0.000113826,0.0001962775],"domain_scores_gemma":[0.9995426,0.000005518862,0.00006668748,0.0002779145,0.00003706119,0.00007021832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000405009,0.00006641645,0.02723845,0.00008692079,0.000007506108,0.00001600378,0.00006663185,0.0003689334,0.9717489,5.818506e-7,0.0001778182,0.0001813759],"study_design_scores_gemma":[0.0005450803,0.00003857628,0.01652713,0.00002251478,0.000004550908,0.00003463107,0.00005144003,0.00002262579,0.9820535,0.000002908885,0.0005375174,0.000159478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948845,0.001270563,0.001669131,0.00001317483,0.0001049925,0.0000608938,0.00001529829,0.000007810127,0.00197365],"genre_scores_gemma":[0.998139,0.000116447,0.0002894462,0.00001634816,0.0001194887,0.000006938793,0.00006031491,0.00001747491,0.001234601],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01071132,"threshold_uncertainty_score":0.6172408,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008163567659365172,"score_gpt":0.276267104436523,"score_spread":0.2681035367771579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}