{"id":"W2034017362","doi":"10.1016/j.ucl.2009.11.011","title":"Novel Targeted Therapies for Prostate Cancer","year":2010,"lang":"en","type":"review","venue":"Urologic Clinics of North America","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"Medicine; Prostate cancer; Androgen receptor; Signal transduction; Tyrosine kinase; Cancer research; Cabozantinib; Receptor tyrosine kinase; Prostate; Receptor; Bioinformatics; Oncology; Cancer; Internal medicine; Biology; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002367759,0.000459732,0.002488838,0.0001985001,0.00008302899,0.00001222106,0.0003171045,0.000370432,0.0001303026],"category_scores_gemma":[0.0003633136,0.0002787429,0.0009030448,0.0004159379,0.0005158588,0.00003019788,0.00009380197,0.0008877224,0.00001938752],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005509645,"about_ca_system_score_gemma":0.001277405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006033991,"about_ca_topic_score_gemma":0.00003884711,"domain_scores_codex":[0.9976218,0.00005266192,0.0009066648,0.0005946558,0.000295629,0.0005286299],"domain_scores_gemma":[0.9972224,0.0007462079,0.0008993542,0.0005912698,0.0003547397,0.0001860919],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003579651,0.0003592478,0.001780587,0.005507663,0.0006852016,0.000009936126,0.00005999887,0.000001100593,0.000001477136,0.000002168075,0.0007272522,0.9905074],"study_design_scores_gemma":[0.001272478,0.001936481,0.0003212268,0.0008104556,0.001408746,0.000009011989,0.000007515571,0.00001654287,8.161581e-7,0.0000222431,0.9939482,0.0002462334],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002406953,0.9932704,0.00005636835,0.0004620796,0.0004245419,0.003476448,0.001896175,0.00006091144,0.0001124076],"genre_scores_gemma":[0.00002794848,0.99211,0.002715111,0.0003725745,0.0003034213,0.001369237,0.001480519,0.00007714442,0.001544001],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.993221,"threshold_uncertainty_score":0.9999665,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0958860115552395,"score_gpt":0.4227895161005104,"score_spread":0.3269035045452709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}