{"id":"W2034029599","doi":"10.1016/j.addr.2011.05.021","title":"Targeting dendritic cells with nano-particulate PLGA cancer vaccine formulations","year":2011,"lang":"en","type":"review","venue":"Advanced Drug Delivery Reviews","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":297,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"PLGA; Immune system; Cancer vaccine; Cancer immunotherapy; Antigen; Dendritic cell; Immunotherapy; Cancer; Adjuvant; Immunology; Cancer research; Tumor antigen; Medicine; Biology; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0005504326,0.001019893,0.003365165,0.0002506345,0.0004867814,0.00003004741,0.0006244224,0.0004128354,0.001661824],"category_scores_gemma":[0.00006451704,0.0006871239,0.0008310366,0.0005189173,0.0001283722,0.0004108532,0.0001382336,0.0008120884,0.002361644],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001815224,"about_ca_system_score_gemma":0.000313484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009202742,"about_ca_topic_score_gemma":0.00005555505,"domain_scores_codex":[0.9953168,0.001107171,0.001722025,0.000808806,0.00005695052,0.0009882245],"domain_scores_gemma":[0.9971931,0.0003995065,0.001232229,0.0009539425,0.0001658905,0.00005534128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001732528,0.0001115634,0.00000347496,0.004958502,0.0007034414,0.00000908309,0.0001983556,0.00001456855,0.003467591,0.00005315194,0.002388763,0.9879183],"study_design_scores_gemma":[0.0008458662,0.0001051449,0.000001310329,0.01917513,0.001533217,0.00008712772,0.00001783088,7.402417e-7,0.001489619,0.00001031149,0.9758699,0.0008638276],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002061181,0.9955139,0.0001227031,0.00001282713,0.001167062,0.002620114,0.00009633052,0.0001246741,0.0001363257],"genre_scores_gemma":[0.00003590911,0.9897248,0.0007299573,0.0001712586,0.00005963668,0.001163048,0.000431022,0.0001495367,0.007534906],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9870544,"threshold_uncertainty_score":0.999558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02866309988347297,"score_gpt":0.2945951771338752,"score_spread":0.2659320772504022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}