{"id":"W2034060255","doi":"10.1074/jbc.m110.192344","title":"The Proprotein Convertase PC7","year":2010,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Proprotein convertase; Chemistry; PCSK9; Biochemistry; Cholesterol; Lipoprotein; LDL receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003467961,0.00008945102,0.0001014065,0.000004473502,0.00008378777,0.00001958721,0.0002444852,0.0002204393,0.0000965071],"category_scores_gemma":[0.0001705772,0.00004744059,0.000148686,0.0000239683,0.0001403812,0.000001815963,0.00002548866,0.0003222021,0.00000310958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003519458,"about_ca_system_score_gemma":0.00005348627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":9.607995e-7,"about_ca_topic_score_gemma":0.000002946917,"domain_scores_codex":[0.9993824,0.00001607573,0.0002522609,0.0001066352,0.0001033876,0.0001391923],"domain_scores_gemma":[0.999448,0.00001495679,0.0001649087,0.0001648721,0.0001172101,0.00009006158],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000146855,0.0000327673,0.003112192,0.000005131318,0.00001951411,0.0000126906,0.000004116312,5.23413e-7,0.9953097,0.00001399833,0.0001437779,0.00119877],"study_design_scores_gemma":[0.0002472284,0.0001180498,0.001382859,0.000003438171,0.000006512188,0.0001328627,0.00002342478,0.0000035445,0.8277941,0.0001232419,0.1700965,0.00006830977],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978452,0.000505028,0.000543779,0.0002827836,0.0001664098,0.00004765,0.00000339421,0.000003196164,0.0006025716],"genre_scores_gemma":[0.9984406,0.000223605,0.000182802,0.00006059479,0.0006158742,0.000002383079,0.00008449755,0.000005177764,0.0003844159],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1699527,"threshold_uncertainty_score":0.1934571,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009295888764422876,"score_gpt":0.219614346695865,"score_spread":0.2103184579314421,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}