{"id":"W2034119200","doi":"10.1103/physrevlett.96.198102","title":"Sequential Recruitment and Combinatorial Assembling of Multiprotein Complexes in Transcriptional Activation","year":2006,"lang":"en","type":"article","venue":"Physical Review Letters","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"DNA; Kinetics; Kinetic energy; Dissociation (chemistry); Transcription (linguistics); Biophysics; Computational biology; Biology; Physics; Chemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008038339,0.00007462085,0.0001445253,0.00001380267,0.00001549975,0.000005608133,0.00004835527,0.00001202638,0.000001584986],"category_scores_gemma":[0.000008798941,0.00007218587,0.00005444531,0.00003948198,0.00003344061,0.000003069234,0.00001880921,0.0000429486,4.028236e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001323054,"about_ca_system_score_gemma":0.00001014851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005628584,"about_ca_topic_score_gemma":0.000007721022,"domain_scores_codex":[0.9994949,0.0000408435,0.0001640015,0.000137688,0.00007979269,0.00008280421],"domain_scores_gemma":[0.9998151,0.000008588262,0.00006626081,0.00007864273,0.00001648991,0.00001492631],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001123611,0.00007882821,0.0003822633,0.0001901374,0.00000737761,2.365181e-7,0.00000701328,0.000214861,0.9974581,0.001188682,0.00006720398,0.0003940504],"study_design_scores_gemma":[0.004738394,0.0004522861,0.07051571,0.002003055,0.0001173549,0.000007492346,0.0000224062,0.008895632,0.8920477,0.004517524,0.01580929,0.0008731664],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975386,0.0008426388,0.0007101838,0.0005192194,0.00003698084,0.0003171507,0.000007414314,0.00000199233,0.00002580506],"genre_scores_gemma":[0.9985369,0.0004277921,0.00037396,0.0003759615,0.0001238338,0.0000360825,0.0001173432,0.000006736475,0.000001361685],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1054104,"threshold_uncertainty_score":0.2943654,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02664810854133294,"score_gpt":0.2925663060439598,"score_spread":0.2659181975026269,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}