{"id":"W2034175695","doi":"10.1212/wnl.0b013e3181fc27e4","title":"Magnetic resonance spectroscopy biomarkers in premanifest and early Huntington disease","year":2010,"lang":"en","type":"article","venue":"Neurology","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":117,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institutes of Health; IXICO; Monash University; Universität Ulm; University of Oxford; U.S. Public Health Service; CHDI Foundation","keywords":"Medicine; Internal medicine; Huntington's disease; Biomarker; Putamen; Magnetic resonance imaging; Psychology; Gastroenterology; Pathology; Disease; Biology; Radiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002792921,0.0003959589,0.000450845,0.0005930668,0.0002870855,0.0003713477,0.0001460783,0.0004725028,0.0009204114],"category_scores_gemma":[0.0006033554,0.0001627856,0.0001066471,0.0002964977,0.0001879768,0.0002195909,0.0002483387,0.0002115999,0.0001200788],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002429948,"about_ca_system_score_gemma":0.0001049286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001971475,"about_ca_topic_score_gemma":0.004278082,"domain_scores_codex":[0.9999152,0.00001087956,0.00001250116,0.00003008916,0.0000168744,0.00001431022],"domain_scores_gemma":[0.9997231,0.00004341975,0.0001290184,0.00001156266,0.00003785336,0.00005495454],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003241169,0.0002330141,0.963432,0.00007080511,0.0002110277,0.000761112,0.0003393276,0.0001092167,0.02216296,0.00004121999,0.0001574279,0.009240706],"study_design_scores_gemma":[0.0000199154,0.0003316652,0.9983595,0.00000416397,0.00002656698,0.0004286174,0.00007349038,0.00006300315,0.000562538,0.00002543895,0.0001028166,0.000002376739],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99939,0.0003876853,0.00002829941,0.000008871298,0.000001446975,0.000004258509,0.00007615213,0.000001986921,0.0001012594],"genre_scores_gemma":[0.999276,0.0001353726,0.0001258892,0.00002460596,0.00000552716,0.000006883268,0.0002327655,9.384158e-7,0.0001919857],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001971475,"threshold_uncertainty_score":0.003920019,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009720576603697281,"score_gpt":0.2412342987924631,"score_spread":0.2315137221887658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}