{"id":"W2034204487","doi":"10.1111/j.1528-1167.2008.01858.x","title":"Polymorphism of the MDR1/ABCB1 C3435T drug‐transporter and resistance to anticonvulsant drugs: A meta‐analysis","year":2009,"lang":"en","type":"review","venue":"Epilepsia","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Odds ratio; Internal medicine; Medicine; Confidence interval; Anticonvulsant; Genotype; Epilepsy; Genotyping; Meta-analysis; Cohort; Pharmacology; Cohort study; Gastroenterology; Oncology; Biology; Genetics; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009850284,0.002719822,0.0112752,0.003531459,0.0006280425,0.002707626,0.002179549,0.002235829,0.003446256],"category_scores_gemma":[0.01973057,0.001486704,0.03503587,0.006231893,0.0005077101,0.000991522,0.001057756,0.00172442,0.0003449382],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001338554,"about_ca_system_score_gemma":0.001198159,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006918192,"about_ca_topic_score_gemma":0.008215765,"domain_scores_codex":[0.9926211,0.004281749,0.001211226,0.001079919,0.0005127487,0.0002932692],"domain_scores_gemma":[0.983867,0.01226453,0.001918957,0.0007876577,0.0008850674,0.0002767683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.004373027,0.00003872485,0.02305021,0.02491501,0.9416233,0.0003399486,0.00004348998,0.001247376,0.000410713,0.00008571451,0.0004881486,0.003384263],"study_design_scores_gemma":[0.0008109612,0.0002044133,0.01040996,0.001257809,0.9857795,0.0001327525,0.00002332427,0.0006565795,0.0001167095,0.0001232849,0.0004689311,0.00001574294],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1133933,0.8791782,0.002747066,0.0006179925,0.0003423774,0.0004062325,0.002297991,0.0001195457,0.0008973569],"genre_scores_gemma":[0.8373894,0.1555254,0.003197927,0.0006176974,0.0002666736,0.0007560757,0.001611905,0.00006054217,0.0005742986],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0112752,"threshold_uncertainty_score":0.05209386,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03768681997757496,"score_gpt":0.3090829631314392,"score_spread":0.2713961431538642,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}