{"id":"W2034314779","doi":"10.1089/hum.2006.17.929","title":"Deletion of VAI and VAII RNA Genes in the Design of Oncolytic Adenoviruses","year":2006,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ministerio de Ciencia y Tecnología; Oncolytics Biotech","keywords":"Biology; Oncolytic virus; Mutant; RNA; Transduction (biophysics); Phenocopy; Gene; Messenger RNA; Translation (biology); Molecular biology; Virology; Cell biology; Virus; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000388924,0.0004362824,0.0002553356,0.0003599341,0.0001947548,0.0004743417,0.000445173,0.0003120843,0.0003507998],"category_scores_gemma":[0.0002990114,0.0003963429,0.000267943,0.0002080687,0.0003353115,0.0002365121,0.0002602385,0.0006836118,0.0003719075],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003828258,"about_ca_system_score_gemma":0.0003298211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003038348,"about_ca_topic_score_gemma":0.0003910838,"domain_scores_codex":[0.9997469,0.0000539787,0.00004252129,0.00003892585,0.00007140399,0.00004629989],"domain_scores_gemma":[0.9997731,0.00004567927,0.00006807944,0.00004063178,0.00002656877,0.00004596554],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006769591,0.00001874881,0.00015294,0.00002881758,0.000004688669,0.00003165324,0.00001850806,0.0004700341,0.9963619,0.0008002052,0.00002133851,0.002023523],"study_design_scores_gemma":[0.00001451998,0.0001759709,0.000439877,0.000006640963,0.00001836495,0.0002227512,0.0000142324,0.001339952,0.9903245,0.0001437025,0.007293073,0.00000640939],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8984402,0.001465799,0.09620009,0.0001464525,0.00008725619,0.0003804639,0.0005290736,0.0002152321,0.00253545],"genre_scores_gemma":[0.9200804,0.001141219,0.07378539,0.00004311284,0.00001725844,0.0002500169,0.000853096,0.00009291067,0.003736752],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004743417,"threshold_uncertainty_score":0.002777636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04559055890373772,"score_gpt":0.315790973934916,"score_spread":0.2702004150311783,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}