{"id":"W2034360108","doi":"10.1016/j.immuni.2011.03.024","title":"Germinal Center B Cell and T Follicular Helper Cell Development Initiates in the Interfollicular Zone","year":2011,"lang":"en","type":"article","venue":"Immunity","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":471,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Yale University; National Institutes of Health; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Multiple Sclerosis Society of Canada","keywords":"Germinal center; BCL6; Biology; CXCR5; B cell; CD40; Cell biology; Follicular dendritic cells; Naive B cell; Follicular phase; Cell; Immunology; Molecular biology; T cell; Antibody; Antigen-presenting cell; Endocrinology; Cytotoxic T cell; In vitro; Genetics; Immune system","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002410383,0.0002967329,0.0003916046,0.0004579884,0.0004527634,0.0006293929,0.0002886023,0.0004153469,0.002303512],"category_scores_gemma":[0.0002961002,0.0002621053,0.000221757,0.000198721,0.0003310987,0.0007034634,0.0006063548,0.001096171,0.001139215],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004184725,"about_ca_system_score_gemma":0.000312359,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007833765,"about_ca_topic_score_gemma":0.001217914,"domain_scores_codex":[0.9997949,0.0000254233,0.000008930802,0.0000394476,0.00004445609,0.00008680049],"domain_scores_gemma":[0.9997302,0.00003857339,0.00004343683,0.00002166968,0.00005755285,0.000108598],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002767585,0.00001629464,0.001317257,0.00005689342,0.000007041998,0.0002315767,0.0001203932,0.00005245883,0.9878128,0.001678879,0.0001398641,0.008289861],"study_design_scores_gemma":[0.00005728791,0.0003304843,0.06673558,0.00005416352,0.00002996727,0.001014038,0.0004588967,0.0005769426,0.9109783,0.001322712,0.01842762,0.0000139883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9586579,0.007278599,0.01995878,0.0001027449,0.0000838559,0.00005445456,0.0002915539,0.0003818148,0.01319025],"genre_scores_gemma":[0.9901134,0.0009263175,0.004000429,0.00004677896,0.00004163238,0.00003210952,0.0003545995,0.00005031248,0.004434458],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002303512,"threshold_uncertainty_score":0.007705986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02236047499391425,"score_gpt":0.2154626212876178,"score_spread":0.1931021462937036,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}