{"id":"W2034377257","doi":"10.1152/ajplung.00016.2009","title":"Modulation of endocytic trafficking and apical stability of CFTR in primary human airway epithelial cultures","year":2009,"lang":"en","type":"article","venue":"American Journal of Physiology-Lung Cellular and Molecular Physiology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Cystic Fibrosis Foundation Therapeutics; National Institutes of Health; Cystic Fibrosis Foundation","keywords":"Apical membrane; Endocytosis; Cell biology; Endocytic cycle; Apical cell; Endosome; Endoplasmic reticulum; Intracellular; Dynamin; Chemistry; Internalization; Transmembrane protein; Epithelial polarity; Biology; Biochemistry; Cell; Receptor; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003526988,0.0001980871,0.0004687407,0.0001572319,0.0002370786,0.0003584881,0.000233223,0.000314686,0.0008585062],"category_scores_gemma":[0.0001579308,0.0001376134,0.0003322471,0.0002369846,0.0001815249,0.0001988909,0.0002707583,0.0006681351,0.0004358771],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003814268,"about_ca_system_score_gemma":0.0002304461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00150273,"about_ca_topic_score_gemma":0.001857886,"domain_scores_codex":[0.9995777,0.00006840687,0.00006703701,0.00009974863,0.0001157193,0.00007131664],"domain_scores_gemma":[0.9997584,0.00005224656,0.00002162836,0.0000457125,0.00008543421,0.00003654082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005005883,0.00001405953,0.000100626,0.00001762203,0.000002336596,0.00003093812,0.00002211605,0.00002630938,0.9993258,0.00002283454,0.00002197047,0.000365325],"study_design_scores_gemma":[0.00001037028,0.0003050256,0.005923001,0.00000537045,0.00002349637,0.0001891112,0.00005325774,0.0008111892,0.990947,0.00002513042,0.001701398,0.000005672039],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9839584,0.004098502,0.007936562,0.0001682408,0.00006368707,0.0001003418,0.001502544,0.0000839559,0.002087821],"genre_scores_gemma":[0.9851703,0.002368217,0.007466247,0.0001424051,0.00002778895,0.0001375268,0.001858779,0.00003703846,0.002791659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00150273,"threshold_uncertainty_score":0.002987981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006550864190121727,"score_gpt":0.2799651342847149,"score_spread":0.2734142700945931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}