{"id":"W2034413092","doi":"10.1039/c4cc07153k","title":"An orthogonal photolabile linker for the complete “on-support” synthesis/fast deprotection/hybridization of RNA","year":2014,"lang":"en","type":"article","venue":"Chemical Communications","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Linker; RNA; Polystyrene; Chemistry; Solid-phase synthesis; Combinatorial chemistry; Photodissociation; Phase (matter); Organic chemistry; Polymer; Biochemistry; Computer science; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002496999,0.0005107146,0.0002639083,0.0002270713,0.0003142165,0.0002328058,0.0005081141,0.0004644633,0.003050086],"category_scores_gemma":[0.0002023236,0.0003558207,0.0003546933,0.0001800251,0.0001604009,0.0002198934,0.0003637229,0.0009139542,0.002463859],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002151083,"about_ca_system_score_gemma":0.0004642124,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002320007,"about_ca_topic_score_gemma":0.0005025019,"domain_scores_codex":[0.9998094,0.00002111019,0.00001369624,0.0000513064,0.00006799328,0.00003656566],"domain_scores_gemma":[0.9998497,0.00003111054,0.00003104007,0.00003505072,0.00002286325,0.00003021304],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003323631,0.00001965336,0.00002812995,0.00006400378,0.000002689512,0.0000545449,0.00001063512,0.00003439281,0.9961671,0.0001928017,0.00009544878,0.003297253],"study_design_scores_gemma":[0.00001150573,0.0001307733,0.0003987043,0.000005675222,0.000009270224,0.0003289915,0.000005327322,0.00030851,0.9893382,0.00005893539,0.009393854,0.0000102805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6079053,0.003916025,0.3698026,0.0004331039,0.0004339912,0.001141485,0.002099853,0.003148945,0.01111876],"genre_scores_gemma":[0.6824965,0.003353272,0.2902019,0.0004189938,0.0001110862,0.00146136,0.004279371,0.0005551644,0.01712234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003050086,"threshold_uncertainty_score":0.01020354,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03243925992509822,"score_gpt":0.289254218241851,"score_spread":0.2568149583167528,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}