{"id":"W2034541624","doi":"10.1016/j.cell.2005.05.030","title":"Recognition of Antimicrobial Peptides by a Bacterial Sensor Kinase","year":2005,"lang":"en","type":"article","venue":"Cell","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":558,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Biology; Antimicrobial peptides; Innate immune system; Signal transduction; Biochemistry; Peptide; Cell biology; Mutant; Transduction (biophysics); Antimicrobial; Microbiology; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001785666,0.0002918026,0.0001886994,0.0001252059,0.000171394,0.0005477149,0.0001603914,0.0002951532,0.001142276],"category_scores_gemma":[0.0001825831,0.0001187164,0.0002168968,0.00008869196,0.0001827578,0.0006402258,0.0002645202,0.0004924221,0.0005328209],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004482932,"about_ca_system_score_gemma":0.000203999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001606195,"about_ca_topic_score_gemma":0.0002044309,"domain_scores_codex":[0.9999214,0.00001346172,0.000004674901,0.00001517102,0.00001646465,0.00002883664],"domain_scores_gemma":[0.9999233,0.00001978082,0.00001372219,0.000007964813,0.00001248175,0.00002268354],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004241345,0.00002962469,0.0003622969,0.00004715156,0.000006209483,0.0001362194,0.00001535054,0.0002267903,0.9941109,0.001241035,0.000115553,0.003284795],"study_design_scores_gemma":[0.00003332114,0.0002058338,0.003347845,0.00001148863,0.00001197201,0.0007450262,0.00006457754,0.004530429,0.9857518,0.0008705577,0.004416985,0.00001012179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862991,0.003790895,0.005571904,0.0004136527,0.00009768965,0.00001860979,0.0001615499,0.00004413013,0.003602356],"genre_scores_gemma":[0.9923442,0.001518908,0.002724353,0.0001126648,0.00002918351,0.00001319852,0.0002558102,0.000007291892,0.002994474],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001142276,"threshold_uncertainty_score":0.003821254,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01050885150653023,"score_gpt":0.2032125283194319,"score_spread":0.1927036768129016,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}