{"id":"W2034545642","doi":"10.1523/jneurosci.2057-04.2004","title":"Glycogen Synthase Kinase-3β Phosphorylates Bax and Promotes Its Mitochondrial Localization during Neuronal Apoptosis","year":2004,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":362,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Medical Research and Materiel Command; National Institute of Neurological Disorders and Stroke; U.S. Department of Defense; National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; U.S. Department of Veterans Affairs","keywords":"GSK-3; Biology; Cell biology; Phosphorylation; Mitochondrion; GSK3B; HEK 293 cells; Transfection; Apoptosis; Molecular biology; Biochemistry; Receptor; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001270936,0.0002631307,0.0001799044,0.0001686283,0.0001393833,0.0002236847,0.0001028912,0.0001292552,0.001064128],"category_scores_gemma":[0.0001059981,0.0001294636,0.0002475778,0.0001479778,0.0001959441,0.0002107723,0.0001925149,0.0004537108,0.0004124933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002688276,"about_ca_system_score_gemma":0.0002012487,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002251277,"about_ca_topic_score_gemma":0.0003378488,"domain_scores_codex":[0.9999355,0.00001014432,0.000007053465,0.00001024413,0.00001659634,0.00002044165],"domain_scores_gemma":[0.9999392,0.0000055407,0.0000218375,0.000006690567,0.000007673297,0.0000191279],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003285313,0.00002657412,0.0006212892,0.00006403408,0.00000897245,0.0001469738,0.00003664516,0.00004491829,0.9968364,0.0001357142,0.00008015169,0.001669645],"study_design_scores_gemma":[0.00009605723,0.00032548,0.02853512,0.0000208046,0.00002901976,0.001207661,0.00009642334,0.0009337186,0.9656195,0.0003570927,0.002770525,0.000008579354],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935299,0.003064178,0.001683497,0.0001316344,0.0000492227,0.00001527845,0.0001362429,0.0000698834,0.001320243],"genre_scores_gemma":[0.9964545,0.001484351,0.0005755713,0.0000464252,0.00001259458,0.00002415673,0.0002407092,0.000008777754,0.001152987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001064128,"threshold_uncertainty_score":0.003559828,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0093696519230582,"score_gpt":0.2271239780442252,"score_spread":0.217754326121167,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}