{"id":"W2034679216","doi":"10.1128/aac.49.7.2887-2894.2005","title":"Efficacy of the Antiadhesin Octyl <i>O</i> -(2-Acetamido-2-Deoxy-β- <scp>d</scp> - Galactopyranosyl)-(1-4)-2- <i>O</i> -Propyl-β- <scp>d</scp> -Galactopyranoside (Fimbrigal-P) in a Rat Oral Candidiasis Model","year":2005,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Helix Biopharma (Canada); University of Saskatchewan","funders":"University of Alberta","keywords":"Disaccharide; Candida albicans; Immunogenicity; In vivo; Chemistry; Microbiology; In vitro; Bioavailability; Glycoside; Pharmacology; Biochemistry; Biology; Antigen; Stereochemistry; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001251529,0.0004771666,0.0003109323,0.0001761637,0.0001136778,0.0002058493,0.0002882578,0.0003445793,0.0007735769],"category_scores_gemma":[0.0001560377,0.0001622553,0.0002336777,0.0001377434,0.0002448656,0.0002097699,0.00008246036,0.0005875167,0.0001561544],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001693263,"about_ca_system_score_gemma":0.0002792653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008502023,"about_ca_topic_score_gemma":0.0009847761,"domain_scores_codex":[0.9998661,0.00002979501,0.00001020329,0.00001990743,0.00003813922,0.00003572957],"domain_scores_gemma":[0.999842,0.00002684363,0.00005270636,0.00001561749,0.00001711647,0.00004561507],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001245071,0.0004484328,0.0001574532,0.00008181109,0.00001504865,0.00003141352,0.00001668435,0.0001416297,0.9932621,0.00004047935,0.00003168501,0.004528231],"study_design_scores_gemma":[0.00007659985,0.01084182,0.002547519,0.000006558699,0.00004198551,0.00007101719,0.00001513653,0.0003938719,0.9855344,0.000009012013,0.0004561301,0.000005956776],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981179,0.0008134774,0.0003740187,0.00003134714,0.00002106435,0.00002423563,0.00008108473,0.00002785765,0.0005090088],"genre_scores_gemma":[0.9961641,0.001216337,0.0009494324,0.00002874034,0.00002025722,0.0000340922,0.0001445432,0.000008245924,0.001434259],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008502023,"threshold_uncertainty_score":0.002587855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01649652825213732,"score_gpt":0.2613073385320678,"score_spread":0.2448108102799305,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}