{"id":"W2034710129","doi":"10.1016/j.bmc.2004.10.002","title":"Photocontrol of nitric oxide production in cell culture using a caged isoform selective inhibitor","year":2004,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Advanced Fluorescence Microscopy Techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University; University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Nitric oxide; Nitric oxide synthase; Cell culture; In vivo; IC50; Biochemistry; In vitro; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001601704,0.0002237353,0.0002502839,0.0000449623,0.00004809612,0.000004948032,0.0001860266,0.000285249,0.000009903329],"category_scores_gemma":[0.0002116385,0.0002096896,0.00006360447,0.0003431124,0.0001543946,0.000009466359,0.00006071863,0.000282423,0.000001029395],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002246802,"about_ca_system_score_gemma":0.0003007131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007844251,"about_ca_topic_score_gemma":0.000008182487,"domain_scores_codex":[0.9987298,0.00001747228,0.0003351448,0.0004389909,0.0001833576,0.0002951883],"domain_scores_gemma":[0.9992876,0.000003834491,0.0001992385,0.0002876685,0.0001457722,0.00007589301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001473946,0.0001411743,0.0007150333,0.0001237473,0.00001260875,0.000006781906,0.0001200062,0.00002119765,0.998512,3.431111e-7,0.0001251108,0.00007459788],"study_design_scores_gemma":[0.001107759,0.00009804891,0.0003350082,0.0001491785,0.00002543195,0.00006923884,0.0003781775,0.000003568889,0.9974166,0.0000593208,0.0001563917,0.000201266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956818,0.0009974355,0.002540498,0.00002959451,0.00003738394,0.0005080383,0.000009836362,0.00002810673,0.0001673012],"genre_scores_gemma":[0.9930809,0.0000989268,0.006279164,0.00004497515,0.0002695218,0.00003740718,0.00003645265,0.00003046064,0.0001221785],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003738665,"threshold_uncertainty_score":0.8550892,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005957678458226131,"score_gpt":0.2518535193365031,"score_spread":0.245895840878277,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}