{"id":"W2034753187","doi":"10.1074/jbc.m709244200","title":"Disruption of the Ugt1 Locus in Mice Resembles Human Crigler-Najjar Type I Disease","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Neonatal Health and Biochemistry","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier universitaire de Québec","funders":"National Institute of Environmental Health Sciences; U.S. Public Health Service; Tobacco-Related Disease Research Program","keywords":"Locus (genetics); Genetics; Disease; Medicine; Biology; Gene; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003059798,0.001512274,0.0005997428,0.001500065,0.000545922,0.0006348208,0.0005566462,0.001432065,0.004628971],"category_scores_gemma":[0.0003678018,0.0005868101,0.0008298742,0.0006453884,0.0009326809,0.0003781769,0.000582772,0.001487002,0.001178457],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005873437,"about_ca_system_score_gemma":0.0003338897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007622645,"about_ca_topic_score_gemma":0.000936078,"domain_scores_codex":[0.9994023,0.00008540068,0.00007540078,0.0002484386,0.00009908911,0.00008932553],"domain_scores_gemma":[0.9996151,0.00004201732,0.0001897746,0.00003794548,0.00001673319,0.00009838189],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008397733,0.0003209928,0.002002179,0.0001556085,0.00007554943,0.004163835,0.0001808471,0.0005226839,0.9850001,0.001534423,0.0007435272,0.004460374],"study_design_scores_gemma":[0.0008523201,0.004694252,0.05719822,0.0002370008,0.000410494,0.09176632,0.0004110403,0.006134569,0.7874713,0.001918787,0.0487414,0.0001643317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9692598,0.00230991,0.01782886,0.0005746431,0.0002492449,0.0004102258,0.003323493,0.001186029,0.004857869],"genre_scores_gemma":[0.9735632,0.002215586,0.01282211,0.0004064554,0.00005481841,0.0003825054,0.003335694,0.0003303315,0.006889347],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004628971,"threshold_uncertainty_score":0.01548553,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05623058082111472,"score_gpt":0.3338051333711806,"score_spread":0.2775745525500659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}