{"id":"W2034805962","doi":"10.1016/j.atherosclerosis.2008.08.001","title":"Efficacy and safety of ursodeoxycholic acid in primary, type IIa or IIb hypercholesterolemia: A multicenter, randomized, double-blind clinical trial","year":2008,"lang":"en","type":"article","venue":"Atherosclerosis","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"The Scarborough Hospital; University of Toronto; Montreal Clinical Research Institute; University of Alberta; St. Michael's Hospital","funders":"","keywords":"Ursodeoxycholic acid; Medicine; Placebo; Internal medicine; Gastroenterology; Cholesterol; Primary biliary cirrhosis; Adverse effect; Bile acid; Randomized controlled trial; Clinical endpoint; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002726543,0.002138756,0.005701026,0.0005329057,0.0009800153,0.001514078,0.0008509799,0.003126903,0.004394967],"category_scores_gemma":[0.003050406,0.001123461,0.002127258,0.0006307936,0.002320711,0.001292246,0.0005434029,0.002984117,0.0008682047],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000744733,"about_ca_system_score_gemma":0.001448767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001068151,"about_ca_topic_score_gemma":0.001200256,"domain_scores_codex":[0.9987177,0.0006952793,0.000103665,0.0002311592,0.00007915378,0.0001730893],"domain_scores_gemma":[0.9982102,0.0004712801,0.0003898516,0.0001932228,0.0001424489,0.0005930213],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9927616,0.002205453,0.0005008226,0.0001432047,0.0004480617,0.00001751705,0.00002503856,0.00006109883,0.001412611,0.0000266359,0.0001327909,0.002265231],"study_design_scores_gemma":[0.9594371,0.03749352,0.001708401,0.00001455995,0.0005665901,0.00001875013,0.00001608063,0.0001697997,0.0003477613,0.00005551905,0.0001598128,0.00001207763],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992978,0.003123711,0.0004606764,0.0004575026,0.0003421945,0.001287742,0.0004268255,0.00005984441,0.0008633635],"genre_scores_gemma":[0.9927139,0.001706184,0.0007937574,0.0007222752,0.0006077241,0.001403371,0.0006081624,0.00002316187,0.001421593],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005701026,"threshold_uncertainty_score":0.01470268,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1565442151166692,"score_gpt":0.3722057419089629,"score_spread":0.2156615267922937,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}