{"id":"W2034805962","doi":"10.1016/j.atherosclerosis.2008.08.001","title":"Efficacy and safety of ursodeoxycholic acid in primary, type IIa or IIb hypercholesterolemia: A multicenter, randomized, double-blind clinical trial","year":2008,"lang":"en","type":"article","venue":"Atherosclerosis","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"The Scarborough Hospital; University of Toronto; Montreal Clinical Research Institute; University of Alberta; St. Michael's Hospital","funders":"","keywords":"Ursodeoxycholic acid; Medicine; Placebo; Internal medicine; Gastroenterology; Cholesterol; Primary biliary cirrhosis; Adverse effect; Bile acid; Randomized controlled trial; Clinical endpoint; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009586567,0.0002460137,0.001272596,0.0001123723,0.00009375292,0.00001514258,0.0001720653,0.000241208,0.0001159913],"category_scores_gemma":[0.0004371869,0.0001749883,0.0002935696,0.0002905248,0.0005407115,0.0001369008,0.0001470256,0.0004462525,0.00002215197],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006264028,"about_ca_system_score_gemma":0.0002008473,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002930412,"about_ca_topic_score_gemma":0.00001186536,"domain_scores_codex":[0.9975588,0.0003854978,0.001072045,0.0003889356,0.0002922844,0.0003024077],"domain_scores_gemma":[0.9982929,0.0005649767,0.0002419466,0.0005492573,0.00011179,0.0002390919],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9369405,0.002309468,0.05564355,0.00006431925,0.0002019187,0.000006267104,0.000715146,7.338041e-7,0.001818504,0.000005025114,0.00008258277,0.002211982],"study_design_scores_gemma":[0.6606492,0.0009722926,0.3373286,0.0002161385,0.0002924146,0.000008754311,0.00003198353,0.00002434189,0.0002000618,0.000001819666,0.0001581123,0.0001163198],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960001,0.0005957102,0.00001486832,0.0001993417,0.0002864953,0.002536497,0.00001399924,0.0000347607,0.0003182651],"genre_scores_gemma":[0.9911503,0.007366341,0.000417491,0.0005348423,0.0001579022,0.00005711275,0.00003270851,0.00003686796,0.0002463934],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.281685,"threshold_uncertainty_score":0.7135817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1565442151166692,"score_gpt":0.3722057419089629,"score_spread":0.2156615267922937,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}