{"id":"W2034812820","doi":"10.1016/j.radonc.2014.05.001","title":"Epigenetics in radiotherapy: Where are we heading?","year":2014,"lang":"en","type":"review","venue":"Radiotherapy and Oncology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Radiation therapy; Epigenetics; Medicine; Histone deacetylase; Epigenetic therapy; Histone deacetylase inhibitor; Cancer research; Cancer; Clinical trial; Bioinformatics; Oncology; Histone; Internal medicine; DNA methylation; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001126486,0.0008000394,0.001664206,0.001224027,0.0003874163,0.001363826,0.001238292,0.002348264,0.002934219],"category_scores_gemma":[0.00135365,0.0003298158,0.0003874449,0.001953344,0.001152456,0.002104159,0.0009814472,0.002771004,0.001338226],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001128435,"about_ca_system_score_gemma":0.001692556,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001825896,"about_ca_topic_score_gemma":0.004438548,"domain_scores_codex":[0.9997534,0.00006604777,0.00002877593,0.00003888232,0.00008506711,0.00002782066],"domain_scores_gemma":[0.9994336,0.0003034819,0.00005975572,0.000016486,0.0001300264,0.00005665846],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009463319,0.0000428401,0.0002864843,0.009230448,0.00008677954,0.0002044067,0.00008323204,0.0005254019,0.001349214,0.007134986,0.08059807,0.9003634],"study_design_scores_gemma":[0.00001684564,0.00004406729,0.0006040412,0.002652277,0.00008774674,0.000826618,0.00008462901,0.0001126303,0.0003238443,0.004378937,0.9908469,0.00002155387],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003049539,0.9984021,0.0001149705,0.0007942342,0.0002990232,0.000001290677,0.000006341421,0.00000333387,0.0003482471],"genre_scores_gemma":[0.0004178596,0.9980508,0.0001379805,0.0004461086,0.0005265595,0.0000027114,0.00001117384,0.000001025893,0.0004058138],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002934219,"threshold_uncertainty_score":0.009815931,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0306224713391508,"score_gpt":0.3578515768519503,"score_spread":0.3272291055127995,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}