{"id":"W2034819890","doi":"10.1371/journal.pone.0031346","title":"The BRG1 Chromatin Remodeler Protects Against Ovarian Cysts, Uterine Tumors, and Mammary Tumors in a Lineage-Specific Manner","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; University of British Columbia","funders":"National Cancer Institute; National Institutes of Health; Canadian Institutes of Health Research; Canadian Breast Cancer Research Alliance; American Institute for Cancer Research","keywords":"SMARCA4; Mammary gland; Biology; Cancer research; SWI/SNF; Chromatin remodeling; Chromatin; Gene; Genetics; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001155312,0.0002703569,0.0002566705,0.0003408479,0.0001042692,0.0002474689,0.0002591429,0.000306152,0.001445515],"category_scores_gemma":[0.00009471951,0.0001891827,0.0001717357,0.0001225478,0.0001674855,0.0001431074,0.0001743993,0.0005901202,0.0003958249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001439902,"about_ca_system_score_gemma":0.0002127406,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005687144,"about_ca_topic_score_gemma":0.001075279,"domain_scores_codex":[0.9999009,0.00001249403,0.00000848474,0.00002321063,0.00002439645,0.00003043073],"domain_scores_gemma":[0.9998717,0.00001056746,0.00004493856,0.00002195633,0.00001040759,0.00004046208],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001411069,0.00003533224,0.0001414912,0.00002043393,0.000005560431,0.00001683588,0.00000660242,0.00002888021,0.99784,0.00004806018,0.00004370375,0.001671985],"study_design_scores_gemma":[0.00009745212,0.001060124,0.01153809,0.00001510925,0.000039556,0.0002777243,0.00003312664,0.000644691,0.9807981,0.00007868361,0.005410647,0.000006823133],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941416,0.002265672,0.001394186,0.0001746377,0.00003394689,0.00002314484,0.0004242813,0.000243618,0.001298987],"genre_scores_gemma":[0.9906979,0.001398848,0.00106913,0.0001400885,0.00001351879,0.00004173943,0.0008656356,0.00005354178,0.005719593],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001445515,"threshold_uncertainty_score":0.004835665,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02336623862413226,"score_gpt":0.2270660416200582,"score_spread":0.2036998029959259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}