{"id":"W2034830634","doi":"10.1159/000108612","title":"Telomere Metabolism and Diagnostic Demonstration of Telomere Measurement in the Human Esophagus for Distinguishing Benign from Malignant Tissue by Tissue Quantitative Fluorescence in situ Hybridization","year":2006,"lang":"en","type":"article","venue":"Oncology","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute","funders":"Japan Foundation for Aging and Health","keywords":"Telomere; Esophagus; Fluorescence in situ hybridization; Pathology; Biology; Carcinogenesis; Chromosome instability; Esophageal cancer; In situ hybridization; Carcinoma; Telomerase; Cancer research; Cancer; Medicine; Chromosome; Anatomy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008528497,0.0002233163,0.0006050888,0.0001816102,0.0001163461,0.00002610508,0.0001560586,0.000158001,0.00001259419],"category_scores_gemma":[0.0012441,0.0001820355,0.00003613671,0.000338012,0.0002017558,0.000125554,0.00002845736,0.0002108403,0.000002128438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000167217,"about_ca_system_score_gemma":0.0001481279,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003957285,"about_ca_topic_score_gemma":0.008304261,"domain_scores_codex":[0.9978524,0.0002918074,0.0007024335,0.0004425061,0.0003783288,0.0003324584],"domain_scores_gemma":[0.9981344,0.001080529,0.0002921988,0.0002210295,0.0002115656,0.00006024372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002418634,0.001321458,0.1156483,0.0002417841,0.00004482214,0.0002034505,0.00392129,0.00005286108,0.8381371,0.01294382,0.001431342,0.02581184],"study_design_scores_gemma":[0.00402384,0.00138339,0.7266008,0.0004789943,0.0002437161,0.00004455072,0.002551538,0.0002477833,0.2589386,0.002867934,0.002241796,0.0003770376],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9849343,0.009990051,0.001941397,0.000919072,0.0001484412,0.00147649,0.00008157964,0.00002409214,0.0004846223],"genre_scores_gemma":[0.9954981,0.0001421792,0.003699528,0.0001121992,0.0001358932,0.0001464604,0.0002220827,0.00002197077,0.0000215547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6109525,"threshold_uncertainty_score":0.7423192,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03085817976859538,"score_gpt":0.3163279531356026,"score_spread":0.2854697733670072,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}