{"id":"W2034840474","doi":"10.1139/w06-055","title":"Triclosan inhibition of membrane enzymes and glycolysis of <i>Streptococcus mutans</i> in suspensions and biofilms","year":2006,"lang":"en","type":"article","venue":"Canadian Journal of Microbiology","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Dental and Craniofacial Research","keywords":"Triclosan; Glycolysis; Streptococcus mutans; Pyruvate kinase; Biochemistry; Aldolase A; Enterococcus hirae; ATPase; Microbiology; Enzyme; Chemistry; Lactate dehydrogenase; Biology; Bacteria","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002027181,0.0001345812,0.0005221724,0.0005145366,0.00006233858,0.000005823661,0.00007948556,0.0002393224,0.0001575389],"category_scores_gemma":[0.00004843753,0.0001191486,0.00007504995,0.0001898436,0.00081121,0.00007661348,0.00002068738,0.0002128021,0.000001464464],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002765687,"about_ca_system_score_gemma":0.0002752198,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.01131104,"about_ca_topic_score_gemma":0.03487636,"domain_scores_codex":[0.9988835,0.0001299764,0.0005774156,0.0001374252,0.000009563635,0.0002621146],"domain_scores_gemma":[0.9992251,0.0001315081,0.0003885924,0.00008690952,0.0001217558,0.00004608198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006587564,0.0000326333,0.0167033,0.0000248625,0.00005308688,0.00003473161,0.0001635444,0.00000785646,0.9802788,0.0006360649,0.001590178,0.0004090397],"study_design_scores_gemma":[0.001476548,0.0002833402,0.00880424,0.0001294783,0.00005819649,0.0009943872,0.0005073999,3.194038e-7,0.9844729,0.0001302755,0.003017705,0.0001252174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993019,0.006086562,0.000005723972,0.0002779941,0.0001461226,0.0001071719,0.0001808553,0.000002004028,0.0001745556],"genre_scores_gemma":[0.9994464,0.0002004844,0.00009606068,0.00005946321,0.0000199981,7.79525e-7,0.00004174586,0.000008317817,0.000126777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02356532,"threshold_uncertainty_score":0.9952728,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005672513717199558,"score_gpt":0.1829389232232078,"score_spread":0.1772664095060082,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}