{"id":"W2034863440","doi":"10.1371/journal.pone.0025674","title":"Improved NYVAC-Based Vaccine Vectors","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Sanofi Pasteur; Sanofi; Bill and Melinda Gates Foundation","keywords":"Vaccinia; Virology; Virus; Biology; Viral replication; Modified vaccinia Ankara; Poxviridae; Interferon; Vector (molecular biology); Transduction (biophysics); Gene; Genetics; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003882474,0.0004977384,0.000325818,0.000452193,0.0001756921,0.0005170768,0.0006218161,0.0004790807,0.002102833],"category_scores_gemma":[0.0003538713,0.0002026756,0.0003136314,0.0002314237,0.0002484787,0.0004761352,0.0003430018,0.001497544,0.001057305],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006014535,"about_ca_system_score_gemma":0.0003286194,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005116804,"about_ca_topic_score_gemma":0.0008877385,"domain_scores_codex":[0.9995913,0.00007588723,0.00006518634,0.00007277272,0.0001438442,0.000051085],"domain_scores_gemma":[0.9997991,0.00003647442,0.00006543935,0.00002927734,0.00003954302,0.00003022042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002291909,0.00009267015,0.0001864461,0.0001281264,0.00001153172,0.00005908235,0.00003770172,0.0003306108,0.9899228,0.001553838,0.0002763453,0.007171663],"study_design_scores_gemma":[0.00006232009,0.000665268,0.001830572,0.00003235567,0.00005129275,0.0006544923,0.00003170082,0.002509622,0.9614806,0.0001983774,0.03246305,0.00002031154],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9202971,0.005531504,0.05949437,0.000501079,0.0004073289,0.001076987,0.003780432,0.0005724079,0.008338735],"genre_scores_gemma":[0.8175657,0.005230017,0.1281185,0.0001909087,0.00009447258,0.0006441976,0.01588704,0.000308137,0.03196098],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002102833,"threshold_uncertainty_score":0.007034659,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04714560509650858,"score_gpt":0.2127227246409585,"score_spread":0.1655771195444499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}