{"id":"W2034883288","doi":"10.1016/j.gene.2006.07.032","title":"Stochastic epigenetic silencing of retrotransposons: Does stability come with age?","year":2006,"lang":"en","type":"review","venue":"Gene","topic":"Chromosomal and Genetic Variations","field":"Agricultural and Biological Sciences","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency; University of British Columbia","funders":"BC Cancer Agency; Canadian Institutes of Health Research; Multiple Sclerosis Scientific Research Foundation","keywords":"Biology; Retrotransposon; Epigenetics; Transposable element; Genetics; DNA methylation; Gene silencing; Endogenous retrovirus; Phenotype; Germline; Somatic cell; Long terminal repeat; Gene; Genome; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001188096,0.0007766393,0.002232517,0.000862828,0.0002600758,0.001460546,0.001441931,0.001697105,0.001277054],"category_scores_gemma":[0.001265448,0.0002288974,0.0003179092,0.001592651,0.001169684,0.001807928,0.0005404485,0.001686125,0.001076205],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006492495,"about_ca_system_score_gemma":0.0007932112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008292928,"about_ca_topic_score_gemma":0.001395447,"domain_scores_codex":[0.9997709,0.0000401316,0.00002918375,0.00006367025,0.0000776631,0.00001840132],"domain_scores_gemma":[0.9992939,0.0004197507,0.00007699104,0.00003506914,0.0001346622,0.00003962191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008832652,0.00003313546,0.000541604,0.004983096,0.0001033678,0.0003899037,0.00009113534,0.0004791881,0.005714388,0.008524385,0.0141173,0.9649342],"study_design_scores_gemma":[0.00002387392,0.0001161314,0.001934129,0.00155138,0.0001834633,0.003849817,0.0002306837,0.0003093189,0.003349157,0.01302494,0.975382,0.00004517387],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002195301,0.9978821,0.0005799973,0.0005332057,0.000207251,0.000001421061,0.000009176876,0.000008454876,0.0005588571],"genre_scores_gemma":[0.001880038,0.9964409,0.0003651578,0.0003902458,0.0003215449,0.000003307031,0.00002186288,0.000002578607,0.0005743112],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002232517,"threshold_uncertainty_score":0.006283343,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04145722730537992,"score_gpt":0.2501311570404688,"score_spread":0.2086739297350889,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}