{"id":"W2034951797","doi":"10.1016/j.jviromet.2014.08.003","title":"Flow cytometry-based assay to study HIV-1 gp120 specific antibody-dependent cellular cytotoxicity responses","year":2014,"lang":"en","type":"article","venue":"Journal of Virological Methods","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":65,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut National de Santé Publique du Québec; McGill University Health Centre; Université de Montréal; McGill University; Centre Hospitalier de l’Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Canada Research Chairs; Canada Foundation for Innovation; Pfizer","keywords":"Antibody-dependent cell-mediated cytotoxicity; Flow cytometry; Biology; Effector; Cytotoxicity; Antibody; Monoclonal antibody; Cytometry; Molecular biology; Virology; Immunology; Cell biology; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.01093672,0.0003058842,0.0008787388,0.0005094784,0.000253716,0.00004945799,0.0006214117,0.0003168704,0.001758918],"category_scores_gemma":[0.003375235,0.0001939706,0.0003259352,0.0003920421,0.000176013,0.00006757499,0.0001740989,0.0009778802,0.0009663607],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001169004,"about_ca_system_score_gemma":0.00007379402,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004047027,"about_ca_topic_score_gemma":0.000001030821,"domain_scores_codex":[0.9865551,0.01136882,0.0007953931,0.000411934,0.0002438978,0.0006248509],"domain_scores_gemma":[0.9952396,0.003511312,0.0003241859,0.0004676424,0.0002230584,0.000234211],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004247526,0.002783749,0.02430101,0.000005616796,0.0003654079,0.0004413536,0.0001153116,0.0001382903,0.9356991,0.00003120438,0.0006141338,0.03125728],"study_design_scores_gemma":[0.007728153,0.02173264,0.2581982,0.00003088548,0.0001715717,0.000261749,0.0002220307,0.00007828406,0.6717402,0.0004710959,0.03894434,0.0004207933],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6078069,0.0006009394,0.3901016,0.0005920028,0.0003460546,0.0003106105,0.00002881696,0.00002418022,0.000188867],"genre_scores_gemma":[0.8814687,0.00003043106,0.1177361,0.0002858241,0.0001384537,0.00001466823,0.00001271123,0.00001760734,0.0002955479],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2736617,"threshold_uncertainty_score":0.9998115,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05313105778025829,"score_gpt":0.3944364590566063,"score_spread":0.341305401276348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}