{"id":"W2034953483","doi":"10.4161/cc.23160","title":"Hes1 mediates the different responses of hematopoietic stem and progenitor cells to T cell leukemic environment","year":2013,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"Chinese Academy of Medical Sciences; Ministry of Science and Technology of the People's Republic of China; Chinese Academy of Sciences; National Natural Science Foundation of China; Academy of Medical Sciences","keywords":"Haematopoiesis; HES1; Biology; Stem cell; Progenitor cell; Leukemia; Stem cell factor; Bone marrow; Cell biology; Cancer research; Molecular biology; Immunology; Signal transduction; Notch signaling pathway","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009813403,0.0002545175,0.0001998995,0.0002147151,0.0001316064,0.0003047141,0.0001402844,0.0002223095,0.0015684],"category_scores_gemma":[0.00006171878,0.0001365612,0.0002236389,0.0001017579,0.0001914788,0.0002440866,0.0002647755,0.0004089647,0.0004039865],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002147917,"about_ca_system_score_gemma":0.0001326669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003070093,"about_ca_topic_score_gemma":0.0003645529,"domain_scores_codex":[0.9998959,0.0000104606,0.000007697973,0.00002434936,0.00002157608,0.00003993167],"domain_scores_gemma":[0.9999423,0.000004346156,0.0000148963,0.000003980278,0.000006872046,0.00002751588],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001484365,0.00001384304,0.0005422739,0.00002577492,0.000003492143,0.0000596385,0.00001741947,0.00005119564,0.9977252,0.0001314236,0.00007548696,0.001205899],"study_design_scores_gemma":[0.00001613096,0.0001911607,0.01506806,0.000005700067,0.00001712487,0.0002333132,0.0000740192,0.0009568895,0.9812202,0.00009119291,0.002120893,0.000005281986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946121,0.001289093,0.001968031,0.00008357249,0.00002207736,0.00002575976,0.0004328158,0.00007465906,0.001491883],"genre_scores_gemma":[0.9954636,0.0006643867,0.0004878034,0.00005558211,0.000007653033,0.0000212317,0.0004236919,0.00001388463,0.002862273],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0015684,"threshold_uncertainty_score":0.005246818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01060144000788837,"score_gpt":0.2134159192282129,"score_spread":0.2028144792203246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}