{"id":"W2034953483","doi":"10.4161/cc.23160","title":"Hes1 mediates the different responses of hematopoietic stem and progenitor cells to T cell leukemic environment","year":2013,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"Chinese Academy of Medical Sciences; Ministry of Science and Technology of the People's Republic of China; Chinese Academy of Sciences; National Natural Science Foundation of China; Academy of Medical Sciences","keywords":"Haematopoiesis; HES1; Biology; Stem cell; Progenitor cell; Leukemia; Stem cell factor; Bone marrow; Cell biology; Cancer research; Molecular biology; Immunology; Signal transduction; Notch signaling pathway","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001554677,0.000205759,0.0003264131,0.00007236507,0.00006356129,0.00002084294,0.0001293413,0.00008469385,0.0003220741],"category_scores_gemma":[0.00000594102,0.0001338555,0.00007258804,0.00007450374,0.00010908,0.00004020119,0.00005209731,0.0001223225,0.0004367555],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005956675,"about_ca_system_score_gemma":0.00003839282,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003693926,"about_ca_topic_score_gemma":0.000001103416,"domain_scores_codex":[0.9985887,0.00009763309,0.0003903033,0.0002933472,0.0003510545,0.0002788994],"domain_scores_gemma":[0.9988531,0.0003594628,0.0001029443,0.0004217009,0.00003054135,0.0002321785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009771512,0.00021423,0.006353505,0.0008186639,0.00002011409,0.000009357301,0.003936385,0.00001719007,0.9873974,0.00001064852,0.0005049436,0.0006198893],"study_design_scores_gemma":[0.0008925254,0.0002555226,0.01812923,0.0001033843,0.0001187656,0.0000241323,0.00147596,0.0001654664,0.9783012,0.00005330166,0.0003363654,0.0001441886],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962844,0.0006187136,0.0002061427,0.0004994288,0.0001011264,0.0014244,0.0000118071,0.00003176459,0.0008222111],"genre_scores_gemma":[0.9968121,0.0002116676,0.0004729752,0.0001439747,0.00004904396,0.0001563527,0.000006095964,0.00003508291,0.002112716],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01177573,"threshold_uncertainty_score":0.5613754,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01060144000788837,"score_gpt":0.2134159192282129,"score_spread":0.2028144792203246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}