{"id":"W2034955793","doi":"10.1159/000320180","title":"Smaddening Complexity: The Role of Smad3 in Epithelial-Myofibroblast Transition","year":2010,"lang":"en","type":"review","venue":"Cells Tissues Organs","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Myofibroblast; Epithelial–mesenchymal transition; Extracellular matrix; Cell biology; Fibrosis; Biology; Transforming growth factor; Cancer research; Context (archaeology); Pathology; Transition (genetics); Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001964993,0.000367516,0.0007722209,0.00008969255,0.00006958376,0.00002919691,0.0005729747,0.0004799914,0.0001649293],"category_scores_gemma":[0.0000367234,0.0002868085,0.0002978016,0.0001789825,0.0002698048,0.000003226841,0.0001109963,0.0003402718,0.00005554011],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001636376,"about_ca_system_score_gemma":0.0002105808,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005040392,"about_ca_topic_score_gemma":0.0001361411,"domain_scores_codex":[0.9983432,0.0001859574,0.0005732897,0.0004432407,0.0001699474,0.0002843617],"domain_scores_gemma":[0.9988586,0.00005413513,0.0002962879,0.0006573896,0.00005874203,0.00007486671],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003443901,0.0002836719,0.00002073946,0.006145373,0.0002095196,0.0000170673,0.0009381489,0.00003229194,0.3335971,0.00005640605,0.0002477801,0.6584175],"study_design_scores_gemma":[0.0001098619,0.00005556968,0.000004166768,0.001580575,0.0001614575,0.00001200111,0.00007671888,0.000002633208,0.1701364,0.00005069547,0.8275427,0.0002673243],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003050519,0.9955131,0.0001043187,0.00001104379,0.0001751163,0.0004971157,0.0002509879,0.00001893993,0.0003787892],"genre_scores_gemma":[0.0108933,0.9866079,0.0005415526,0.00002386857,0.0005433925,0.00004938745,0.0009451906,0.0001225072,0.00027288],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8272949,"threshold_uncertainty_score":0.9999584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01898651249666197,"score_gpt":0.2783490206236049,"score_spread":0.2593625081269429,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}