{"id":"W2034992259","doi":"10.1182/blood-2008-02-136374","title":"Paraffin-based 6-gene model predicts outcome in diffuse large B-cell lymphoma patients treated with R-CHOP","year":2008,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":104,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute","keywords":"Diffuse large B-cell lymphoma; Internal medicine; Vincristine; Medicine; Prednisone; Oncology; Rituximab; CHOP; Cyclophosphamide; Anthracycline; Lymphoma; Chemotherapy; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004542022,0.0002983811,0.000459683,0.0001530767,0.00008316349,0.000009694717,0.00008390092,0.0001191239,0.00001419056],"category_scores_gemma":[0.0000233883,0.000210248,0.0001049601,0.0002022805,0.00004320605,0.00005677297,0.00002503307,0.00005634292,0.00006338072],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001562736,"about_ca_system_score_gemma":0.000195298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001081508,"about_ca_topic_score_gemma":0.00004198628,"domain_scores_codex":[0.9983633,0.00003033795,0.0003524159,0.0004115841,0.0003915043,0.00045089],"domain_scores_gemma":[0.9990942,0.00004771099,0.00009792155,0.0004406907,0.00008005123,0.0002393543],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003325069,0.08784653,0.9100614,0.00003347385,0.00008009042,0.001079644,0.0001417781,0.00007897305,0.00007710223,0.000003508268,0.00009129167,0.000173762],"study_design_scores_gemma":[0.2045406,0.0009335032,0.7719616,0.00006820032,0.000324109,0.00002702359,0.000006597821,0.003077418,0.01877741,0.000001498005,0.00007268808,0.000209379],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975258,0.0002190674,0.00001538635,0.00006504917,0.0000214638,0.0006888605,0.0001047556,0.00009680198,0.001262869],"genre_scores_gemma":[0.9978458,0.00006138642,0.0006578402,0.0005082233,0.00002558024,0.0001926061,0.000212677,0.00004729447,0.00044865],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2042081,"threshold_uncertainty_score":0.8573664,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01674366896439497,"score_gpt":0.2244839283498904,"score_spread":0.2077402593854954,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}