{"id":"W2035016472","doi":"10.1007/s00125-010-1681-4","title":"The Framingham and UK Prospective Diabetes Study (UKPDS) risk equations do not reliably estimate the probability of cardiovascular events in a large ethnically diverse sample of patients with diabetes: the Action in Diabetes and Vascular Disease: Preterax and Diamicron-MR Controlled Evaluation (ADVANCE) Study","year":2010,"lang":"en","type":"article","venue":"Diabetologia","topic":"Diabetes, Cardiovascular Risks, and Lipoproteins","field":"Medicine","cited_by":131,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Université de Montréal","funders":"National Health and Medical Research Council; Medical Research Council; Servier; University of Sydney","keywords":"Ethnically diverse; Medicine; United Kingdom Prospective Diabetes Study; Framingham Risk Score; Diabetes mellitus; Internal medicine; Framingham Heart Study; Prospective cohort study; Type 2 diabetes; Disease; Endocrinology; Population; Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.009171295,0.0004248396,0.001452635,0.0001604486,0.0004187639,0.00006252294,0.0002640497,0.0001463361,0.000005217451],"category_scores_gemma":[0.008892449,0.0002250133,0.000295527,0.0005198651,0.0007022598,0.0002414864,0.0002764041,0.0007524944,3.389409e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009292419,"about_ca_system_score_gemma":0.0001221175,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006622548,"about_ca_topic_score_gemma":0.002272242,"domain_scores_codex":[0.9946533,0.001914527,0.0008307357,0.0008298691,0.001183461,0.0005880531],"domain_scores_gemma":[0.9948571,0.002570984,0.0004807991,0.00135333,0.0006076347,0.0001301725],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004233314,0.001527843,0.9676027,0.0001439015,0.002181206,6.516194e-7,0.002483337,0.0004768789,0.00005253902,0.00001348862,5.99131e-7,0.0250935],"study_design_scores_gemma":[0.01751314,0.001226131,0.9712065,0.0001385766,0.003222769,5.003013e-8,0.001157089,0.004328435,0.0001049492,0.0008507735,0.00001054494,0.000241069],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9798491,0.004114396,0.00005350688,0.00005209391,0.0001257213,0.01563445,0.000141461,0.00002566605,0.00000358172],"genre_scores_gemma":[0.9968223,0.0001937311,0.0001615314,0.00001908899,0.00002990281,0.002699614,0.00003790424,0.00003480768,0.000001136774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02485243,"threshold_uncertainty_score":0.999456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01127673101460332,"score_gpt":0.276169894045834,"score_spread":0.2648931630312307,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}