{"id":"W2035043164","doi":"10.1038/nm1604","title":"A GABAergic system in airway epithelium is essential for mucus overproduction in asthma","year":2007,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":206,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; University of Toronto; University of Manitoba; Canada Research Chairs; Health Sciences Centre; Sunnybrook Health Science Centre","funders":"","keywords":"Asthma; Overproduction; Airway; Mucus; Respiratory epithelium; Epithelium; GABAergic; Medicine; Immunology; Biology; Internal medicine; Pathology; Anesthesia; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000317735,0.000390462,0.0005783419,0.0003487253,0.0006054773,0.0007872322,0.0005701018,0.000560139,0.0008295054],"category_scores_gemma":[0.0004210604,0.000351293,0.0005150857,0.0001102452,0.0006131922,0.0004616279,0.0007921808,0.00156973,0.0002751692],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006787133,"about_ca_system_score_gemma":0.0006260241,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00251912,"about_ca_topic_score_gemma":0.00364323,"domain_scores_codex":[0.9996693,0.00005218523,0.00003307363,0.00004466808,0.00008386486,0.0001168095],"domain_scores_gemma":[0.9995599,0.0000464709,0.00009613699,0.00004297589,0.00009349436,0.0001608736],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005191606,0.00003092254,0.002594232,0.0001159325,0.00004877709,0.0005763,0.00003417031,0.0002065603,0.9909589,0.0009729394,0.0002903288,0.003651802],"study_design_scores_gemma":[0.0003533775,0.001041633,0.1437398,0.0001568194,0.0004735159,0.004234666,0.0006497821,0.004877132,0.8334157,0.00165651,0.009350071,0.00005102293],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9779334,0.01155256,0.005712465,0.001320211,0.0003557252,0.00003160107,0.0003101651,0.0001710726,0.002612925],"genre_scores_gemma":[0.9945305,0.001737335,0.002257084,0.0001295712,0.00003535436,0.00001257949,0.0001270188,0.00002587496,0.001144746],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00251912,"threshold_uncertainty_score":0.005008936,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005287769658337419,"score_gpt":0.2912648617790355,"score_spread":0.2859770921206981,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}