{"id":"W2035064666","doi":"10.1038/onc.2012.283","title":"Reduced in vivo lung metastasis of a breast cancer cell line after treatment with Herceptin mAb conjugated to chemotherapeutic drugs","year":2012,"lang":"en","type":"article","venue":"Oncogene","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Institutes of Health; Canadian Institutes of Health Research; Fondation du cancer du sein du Québec","keywords":"In vivo; Trastuzumab; Cytotoxicity; Doxorubicin; Pharmacology; Cancer research; Monoclonal antibody; Metastasis; Antibody-drug conjugate; Metastatic breast cancer; Biology; Cancer; Breast cancer; In vitro; Chemotherapy; Antibody; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001465362,0.0004046354,0.0004603967,0.0002424907,0.0001880103,0.000233287,0.000295353,0.000455396,0.002624582],"category_scores_gemma":[0.0001480662,0.0002545027,0.0002879411,0.0002274522,0.0002021017,0.0002253023,0.0001167886,0.0006785613,0.0004960425],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003753069,"about_ca_system_score_gemma":0.0002777009,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002565994,"about_ca_topic_score_gemma":0.002105074,"domain_scores_codex":[0.999798,0.00004117391,0.00001091431,0.0000328794,0.0000447747,0.00007218848],"domain_scores_gemma":[0.9998964,0.00003085496,0.00001383622,0.00001557707,0.00001648909,0.00002681485],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000400389,0.0001288569,0.00008045835,0.00002653028,0.000007862914,0.00002872045,0.00001392714,0.00009437652,0.9983876,0.00006268284,0.00007416887,0.0006945353],"study_design_scores_gemma":[0.00003254131,0.0004975288,0.001765917,0.000001922351,0.00001556047,0.0000688057,0.00001080371,0.001121939,0.9958572,0.00001567228,0.0006093724,0.000002810426],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950985,0.0009518578,0.001185818,0.0001226102,0.00007320131,0.00002870648,0.0004261667,0.00008747884,0.002025588],"genre_scores_gemma":[0.9925562,0.0004504543,0.0008281932,0.00004217779,0.00001485221,0.00004052827,0.000804975,0.00002496465,0.005237598],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002624582,"threshold_uncertainty_score":0.008780062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03010614607539926,"score_gpt":0.3576470034110102,"score_spread":0.327540857335611,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}