{"id":"W2035191826","doi":"10.1182/blood-2003-06-2118","title":"Lipopolysaccharide initiates a TRAF6-mediated endothelial survival signal","year":2004,"lang":"en","type":"article","venue":"Blood","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Cell biology; Signal transduction; PI3K/AKT/mTOR pathway; Tumor necrosis factor alpha; Kinase; Protein kinase B; Endothelial stem cell; Biology; Lipopolysaccharide; Apoptosis; Cancer research; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002020851,0.0006011219,0.0001800627,0.0003415982,0.0002254202,0.0003940022,0.0001761402,0.0003814502,0.003223416],"category_scores_gemma":[0.000168733,0.0001326379,0.0003898799,0.0001608698,0.0002091113,0.0003814615,0.0003601113,0.000842672,0.001575176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003600013,"about_ca_system_score_gemma":0.0001840539,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001125564,"about_ca_topic_score_gemma":0.00009318671,"domain_scores_codex":[0.9997877,0.00004724442,0.00001579831,0.00002712514,0.0000654109,0.00005657539],"domain_scores_gemma":[0.9998078,0.0000165686,0.00005642339,0.00001845377,0.00004188957,0.00005897093],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002326918,0.00003926771,0.0002055908,0.00007988945,0.000006238977,0.000247155,0.00001330584,0.0000896119,0.9955005,0.0006791935,0.0001249135,0.002781544],"study_design_scores_gemma":[0.00003892489,0.000341867,0.00478686,0.00002000611,0.0000105218,0.001237935,0.00003423633,0.0008684134,0.9829595,0.0005929417,0.00909816,0.0000106223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.931264,0.01368694,0.03923714,0.001005751,0.0005088741,0.0001542951,0.001706052,0.0006126643,0.01182426],"genre_scores_gemma":[0.9725415,0.004859446,0.01041887,0.0002083539,0.0001072819,0.00006471729,0.001693294,0.00002690131,0.01007973],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003223416,"threshold_uncertainty_score":0.01078343,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.012921705596704,"score_gpt":0.2259997264144977,"score_spread":0.2130780208177937,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}