{"id":"W2035240798","doi":"10.1002/cncr.26429","title":"Phase 1 trial of everolimus plus sunitinib in patients with metastatic renal cell carcinoma","year":2011,"lang":"en","type":"article","venue":"Cancer","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":125,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Cancer Institute","keywords":"Sunitinib; Everolimus; Medicine; Renal cell carcinoma; Tyrosine-kinase inhibitor; Internal medicine; Urology; Oncology; Pharmacology; Gastroenterology; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007721812,0.0001603115,0.000406401,0.0001316569,0.00001449593,0.000002387117,0.00006558077,0.00003560722,0.0005334605],"category_scores_gemma":[0.00001178814,0.0001135714,0.00006820898,0.0001816396,0.00006843916,0.00005210654,0.00001770604,0.0001120363,0.000009064267],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002536275,"about_ca_system_score_gemma":0.00032113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007603574,"about_ca_topic_score_gemma":0.00007194919,"domain_scores_codex":[0.9989147,0.00005074315,0.0002998231,0.0002158653,0.0002911523,0.0002276761],"domain_scores_gemma":[0.9992935,0.00002710624,0.0001463272,0.0002802587,0.0001260384,0.0001267878],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6387817,0.01297087,0.3251626,0.0006636376,0.0003806468,0.0008344623,0.006680931,0.00002959796,0.002088818,0.00003997962,0.0007665276,0.01160027],"study_design_scores_gemma":[0.5813705,0.01770897,0.3254411,0.0001492018,0.0006788462,0.000004629493,0.0001451962,0.00003023207,0.07404181,0.00001839931,0.0001871783,0.0002239673],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936687,0.0002987506,0.000009628821,0.00001187,0.0001124492,0.001012752,0.00004319088,0.000009742041,0.004832895],"genre_scores_gemma":[0.9989665,0.000009149589,0.0003772592,0.00005959124,0.00005003891,0.0001300712,0.00003849198,0.000025741,0.0003432074],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.071953,"threshold_uncertainty_score":0.5841019,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06176865617352181,"score_gpt":0.2920891118821515,"score_spread":0.2303204557086297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}