{"id":"W2035240798","doi":"10.1002/cncr.26429","title":"Phase 1 trial of everolimus plus sunitinib in patients with metastatic renal cell carcinoma","year":2011,"lang":"en","type":"article","venue":"Cancer","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":125,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Cancer Institute","keywords":"Sunitinib; Everolimus; Medicine; Renal cell carcinoma; Tyrosine-kinase inhibitor; Internal medicine; Urology; Oncology; Pharmacology; Gastroenterology; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001803181,0.001861804,0.002669417,0.0004161212,0.0005686545,0.0009602695,0.000892179,0.001103533,0.003601092],"category_scores_gemma":[0.0009887457,0.0006389928,0.001172664,0.0003540794,0.0007154727,0.0007520689,0.0003660713,0.002749465,0.0007941353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001333808,"about_ca_system_score_gemma":0.002460014,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001214387,"about_ca_topic_score_gemma":0.003977627,"domain_scores_codex":[0.9995664,0.0001839011,0.00002350973,0.00009168267,0.00004810593,0.00008645098],"domain_scores_gemma":[0.9993268,0.0001144346,0.0001208745,0.00003526509,0.00004741646,0.0003551791],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.805756,0.04980475,0.01241276,0.001750145,0.002547586,0.0006044486,0.0003741308,0.004956384,0.02790358,0.0002898333,0.007743289,0.08585701],"study_design_scores_gemma":[0.73599,0.2445007,0.01241202,0.00004283793,0.0004080784,0.0003928881,0.00003919847,0.001637653,0.002202104,0.0001475021,0.002202327,0.00002469632],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924682,0.002415163,0.0002731916,0.0005910744,0.0001876723,0.001980869,0.0007538193,0.00008897749,0.001241108],"genre_scores_gemma":[0.9911656,0.001479348,0.001014176,0.0007151249,0.0002110248,0.001809849,0.00177338,0.00002106179,0.001810498],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003601092,"threshold_uncertainty_score":0.01204687,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06176865617352181,"score_gpt":0.2920891118821515,"score_spread":0.2303204557086297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}