{"id":"W2035276582","doi":"10.4161/mabs.27828","title":"Comparative reactivity of human IgE to cynomolgus monkey and human effector cells and effects on IgE effector cell potency","year":2014,"lang":"en","type":"article","venue":"mAbs","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Thomas Hospital","funders":"Academy of Medical Sciences; National Institute for Health and Care Research; Cancer Research UK","keywords":"Effector; Immunoglobulin E; Immune system; Biology; Immunology; Antibody; Potency; Receptor; In vitro; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003483336,0.0002604261,0.0006728126,0.0001653977,0.0002561811,0.00001851134,0.00009405227,0.00009780436,0.00004372342],"category_scores_gemma":[0.00004518991,0.0001984467,0.00008101492,0.0001188106,0.0001432378,0.00004279389,0.0001710785,0.0002981887,0.00008742651],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000354609,"about_ca_system_score_gemma":0.00001400001,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001067292,"about_ca_topic_score_gemma":0.00007040391,"domain_scores_codex":[0.9983938,0.00026453,0.0002136779,0.0004239304,0.0003620222,0.0003420092],"domain_scores_gemma":[0.9984762,0.000731982,0.00007757309,0.0002942816,0.00007114658,0.0003488338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000523402,0.0002768913,0.01405536,0.001246913,0.00004506433,0.00003615276,0.000590406,6.144409e-7,0.9787143,0.0003062384,0.001167845,0.003036803],"study_design_scores_gemma":[0.001497194,0.005636908,0.3396095,0.0002775538,0.00004804477,0.000007755082,0.00001470644,0.00004415682,0.6490244,0.00008365054,0.003571534,0.0001845683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991488,0.0001474974,0.00001597019,0.0002236095,0.00007758345,0.0009540496,0.00003575388,0.00002858654,0.007028947],"genre_scores_gemma":[0.9973221,0.00001209989,0.000114706,0.0002099668,0.0001896448,0.00003438733,0.00002702646,0.0000222298,0.002067794],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3296899,"threshold_uncertainty_score":0.8092423,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02041420649055867,"score_gpt":0.3209488151709028,"score_spread":0.3005346086803441,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}