{"id":"W2035276582","doi":"10.4161/mabs.27828","title":"Comparative reactivity of human IgE to cynomolgus monkey and human effector cells and effects on IgE effector cell potency","year":2014,"lang":"en","type":"article","venue":"mAbs","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Thomas Hospital","funders":"Academy of Medical Sciences; National Institute for Health and Care Research; Cancer Research UK","keywords":"Effector; Immunoglobulin E; Immune system; Biology; Immunology; Antibody; Potency; Receptor; In vitro; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005205232,0.00034477,0.0003311823,0.0002542679,0.0001373501,0.0004112931,0.0001532498,0.0003357073,0.002953532],"category_scores_gemma":[0.0005250751,0.0001060715,0.0002607867,0.0001822712,0.000184072,0.000160415,0.000253047,0.0004803943,0.0004820743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002753411,"about_ca_system_score_gemma":0.0001259867,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005756533,"about_ca_topic_score_gemma":0.0007124745,"domain_scores_codex":[0.9995628,0.0001547766,0.00003046425,0.00007927562,0.00009117714,0.00008146281],"domain_scores_gemma":[0.9997646,0.000119318,0.00002167208,0.00004175237,0.00003459742,0.00001804705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006422352,0.00009367835,0.001467071,0.0000814509,0.00003054429,0.00008706862,0.00008463392,0.0001130987,0.9932907,0.00005764535,0.00005492338,0.003997033],"study_design_scores_gemma":[0.00003379052,0.003618652,0.03375679,0.00002398521,0.0001098542,0.001443092,0.0001264162,0.000864839,0.9555107,0.0000847024,0.004417646,0.000009579397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908541,0.00437738,0.002124369,0.00004176409,0.00001456634,0.00004535526,0.0001760003,0.00002663477,0.002339774],"genre_scores_gemma":[0.9958199,0.0008739053,0.001274734,0.00009365098,0.00001780716,0.00005244139,0.0006711992,0.00001583361,0.00118049],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002953532,"threshold_uncertainty_score":0.009880543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02041420649055867,"score_gpt":0.3209488151709028,"score_spread":0.3005346086803441,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}