{"id":"W2035289508","doi":"10.4103/1673-5374.153686","title":"A new look at auranofin, dextromethorphan and rosiglitazone for reduction of glia-mediated inflammation in neurodegenerative diseases","year":2015,"lang":"en","type":"review","venue":"Neural Regeneration Research","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Okanagan University College; University of British Columbia, Okanagan Campus; University of British Columbia","funders":"","keywords":"Auranofin; Microglia; Neuroinflammation; Inflammation; Neurotoxicity; Medicine; Astrocyte; Pharmacology; Neuroscience; Immunology; Central nervous system; Biology; Internal medicine; Toxicity; Rheumatoid arthritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001449967,0.0006083255,0.001376026,0.001737937,0.0004170582,0.0002582322,0.0004576999,0.0004027503,0.00006200068],"category_scores_gemma":[0.003639667,0.0005535839,0.0002672907,0.002008209,0.0002343622,0.0006799939,0.0002785126,0.0006537262,0.00004280084],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004030466,"about_ca_system_score_gemma":0.001077625,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001705351,"about_ca_topic_score_gemma":0.00006607836,"domain_scores_codex":[0.9914569,0.003461409,0.001589696,0.001509755,0.001309522,0.0006727255],"domain_scores_gemma":[0.9959383,0.001424207,0.0007448412,0.0006768124,0.0007193764,0.0004964823],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003449316,0.00007400281,0.000001398088,0.00254868,0.0000110199,0.00001959058,0.0002043302,0.0003198347,0.5747107,0.007672966,0.003489204,0.4106034],"study_design_scores_gemma":[0.002441744,0.001065861,0.000004726949,0.001033072,0.000156409,0.0001582348,0.00003230348,0.01414594,0.6637317,0.002094933,0.3142633,0.0008717935],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01577754,0.9684073,0.002114486,0.001250796,0.001183575,0.01030641,0.0005486567,0.0002465808,0.0001646538],"genre_scores_gemma":[0.001299964,0.9902285,0.0009979092,0.00005846176,0.0009396182,0.001181139,0.0006520122,0.0001796878,0.004462718],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.4097316,"threshold_uncertainty_score":0.9996915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2504112195265635,"score_gpt":0.4402665403741529,"score_spread":0.1898553208475894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}