{"id":"W2035291856","doi":"10.1016/j.ijpharm.2010.01.015","title":"Novel self-associating poly(ethylene oxide)-b-poly(ɛ-caprolactone) based drug conjugates and nano-containers for paclitaxel delivery","year":2010,"lang":"en","type":"article","venue":"International Journal of Pharmaceutics","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":80,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Caprolactone; Ethylene oxide; Drug delivery; Poly ethylene; Paclitaxel; Conjugate; Drug carrier; Chemistry; Oxide; Materials science; Polymer chemistry; Organic chemistry; Polymer; Copolymer; Ethylene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001906789,0.0002447265,0.0003236939,0.0002344137,0.0001430804,0.0002487453,0.0006103643,0.000102246,0.0001006562],"category_scores_gemma":[0.0005045533,0.0002286312,0.0001762086,0.00009644223,0.0001203669,0.0006355551,0.0001087273,0.0004156359,0.00001441992],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002134112,"about_ca_system_score_gemma":0.0003886886,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007269921,"about_ca_topic_score_gemma":0.0000373622,"domain_scores_codex":[0.9976127,0.0000706551,0.0008478091,0.0002576138,0.0007941231,0.0004170749],"domain_scores_gemma":[0.9963098,0.0009985033,0.0009207717,0.0001395248,0.001346308,0.0002851166],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004964668,0.0003122018,0.005595096,0.00002822764,0.0001430355,0.00002393703,0.0003331977,0.0001053123,0.9905276,0.0002921021,0.0001848987,0.001957983],"study_design_scores_gemma":[0.004951247,0.00007909586,0.0004538948,0.0000627347,0.0001490412,0.0001012524,0.0002136842,0.01437047,0.9758084,0.0002014073,0.003354731,0.0002540709],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903183,0.0008107636,0.002927478,0.002674619,0.002777672,0.0002163553,0.0001878451,0.00005263428,0.00003435782],"genre_scores_gemma":[0.9584177,0.00006229954,0.03913886,0.001666031,0.0006218613,0.000009718402,0.000006668919,0.00003746327,0.00003940489],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03621139,"threshold_uncertainty_score":0.9323308,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0192421995355906,"score_gpt":0.3042464334227982,"score_spread":0.2850042338872076,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}