{"id":"W2035319606","doi":"10.1016/j.bbrc.2007.08.072","title":"CD4+ T cell acquisition of the bystander pMHC I colocalizing in the same immunological synapse comprising pMHC II and costimulatory CD40, CD54, CD80, OX40L, and 41BBL","year":2007,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan; Saskatchewan Cancer Agency","funders":"University of Saskatchewan; Medical University of South Carolina","keywords":"CD80; Immunological synapse; Lipid raft; Bystander effect; Cell biology; Major histocompatibility complex; Internalization; T cell; CD40; Biology; Immune system; Cell; Chemistry; Cytotoxic T cell; T-cell receptor; Signal transduction; Immunology; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001073982,0.000330651,0.0002698226,0.0001675338,0.0002380618,0.0004360242,0.0001793045,0.0004903472,0.00618528],"category_scores_gemma":[0.0001586099,0.0001526309,0.0002190664,0.00007530241,0.0001560389,0.0002937104,0.0002456792,0.001404155,0.0008757213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004338037,"about_ca_system_score_gemma":0.0002654552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005822515,"about_ca_topic_score_gemma":0.0009705145,"domain_scores_codex":[0.9997821,0.00002287266,0.00000511189,0.00003549262,0.00002520195,0.0001292112],"domain_scores_gemma":[0.9998958,0.00002122849,0.00001256491,0.00001817562,0.00001215257,0.00004014871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002889411,0.00007403275,0.0003127454,0.00004228884,0.000007355065,0.0001243697,0.00003048154,0.0001995772,0.9950442,0.0004441584,0.0002813601,0.003150403],"study_design_scores_gemma":[0.0002311054,0.001335371,0.01568571,0.00003155346,0.00005727264,0.0009927273,0.0002172976,0.004517068,0.9706664,0.0007882867,0.005461704,0.00001557181],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928592,0.0004808498,0.0006830784,0.000126138,0.00005679309,0.00001791249,0.00006829303,0.00005356778,0.005654226],"genre_scores_gemma":[0.9950013,0.000137397,0.000513572,0.00009612973,0.00004328553,0.00001398156,0.0001037359,0.00001025667,0.004080389],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00618528,"threshold_uncertainty_score":0.02069187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05011416780330295,"score_gpt":0.3376082711017049,"score_spread":0.287494103298402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}