{"id":"W2035320881","doi":"10.1002/art.37816","title":"Tofacitinib (CP‐690,550) in patients with rheumatoid arthritis receiving methotrexate: Twelve‐month data from a twenty‐four–month phase III randomized radiographic study","year":2013,"lang":"en","type":"article","venue":"Arthritis & Rheumatism","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":582,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Pfizer","keywords":"Tofacitinib; Medicine; Placebo; Rheumatoid arthritis; Internal medicine; Interim analysis; Janus kinase inhibitor; Rheumatology; Methotrexate; Randomized controlled trial; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002913237,0.001179279,0.004025195,0.001198791,0.0005999375,0.0007227575,0.001190425,0.0003092186,0.006649234],"category_scores_gemma":[0.001484862,0.00102178,0.0004194584,0.001420511,0.0009333921,0.002736611,0.0006183642,0.001288464,0.0003972668],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001321853,"about_ca_system_score_gemma":0.0003066489,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02399625,"about_ca_topic_score_gemma":0.009030197,"domain_scores_codex":[0.9889212,0.001931345,0.002816079,0.002131558,0.00227767,0.001922136],"domain_scores_gemma":[0.9929296,0.00151315,0.0008274019,0.00306999,0.0005761643,0.001083741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.03473989,0.007009779,0.2948028,0.00005787346,0.002308362,0.0006247791,0.006927511,0.000008387084,0.0001816125,0.000150803,0.005861791,0.6473264],"study_design_scores_gemma":[0.7864444,0.002962967,0.1918631,0.009716433,0.00004906575,0.0001421096,0.002595712,0.001506173,0.00007489921,0.001307057,0.001824928,0.001513164],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9488355,0.03764984,0.0005486203,0.0005385409,0.000407585,0.01005041,0.0007431863,0.0004170553,0.0008092526],"genre_scores_gemma":[0.8570663,0.1350545,0.003504452,0.0001752779,0.00005967734,0.001606518,0.002233388,0.0002113454,0.00008847655],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7517045,"threshold_uncertainty_score":0.9992232,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01977718972046093,"score_gpt":0.2746561175317261,"score_spread":0.2548789278112652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}