{"id":"W2035339370","doi":"10.1038/labinvest.3700701","title":"Normal human primary CD4+ T lymphocytes synthesize and release functional osteoprotegerin in vitro","year":2007,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Université Laval","funders":"","keywords":"Osteoprotegerin; RANKL; Internal medicine; Endocrinology; Immune system; Biology; Molecular biology; Receptor; Immunology; Chemistry; Activator (genetics); Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004688516,0.0007971996,0.0006090776,0.0006974739,0.0003038667,0.0006737637,0.0004447482,0.0005220912,0.004688137],"category_scores_gemma":[0.000930872,0.0002779284,0.000474594,0.0006653472,0.0002983604,0.0003182586,0.0004180155,0.0008648072,0.001873343],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004040701,"about_ca_system_score_gemma":0.0002830334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00105192,"about_ca_topic_score_gemma":0.0008384811,"domain_scores_codex":[0.9994836,0.0001215125,0.00004687733,0.00008679158,0.0001096161,0.000151618],"domain_scores_gemma":[0.9989747,0.0004967754,0.0000564391,0.0001946641,0.0001429229,0.0001345661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001792218,0.0003129988,0.001342672,0.0001621222,0.00002197454,0.000298724,0.0001055834,0.0001549554,0.991104,0.0001189853,0.0003398369,0.004246045],"study_design_scores_gemma":[0.0005049636,0.00325359,0.0201543,0.00002913876,0.0001267364,0.002213886,0.0001986154,0.00120592,0.9637364,0.0002788033,0.00827812,0.00001965271],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9796552,0.00865063,0.005311182,0.0001350106,0.0002629884,0.0001427101,0.001100063,0.0002487536,0.004493554],"genre_scores_gemma":[0.9815795,0.002568455,0.003231992,0.000130763,0.0002107919,0.0001854016,0.006475667,0.00005486316,0.005562537],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004688137,"threshold_uncertainty_score":0.01568341,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006774790503118275,"score_gpt":0.2051733357809746,"score_spread":0.1983985452778564,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}