{"id":"W2035339370","doi":"10.1038/labinvest.3700701","title":"Normal human primary CD4+ T lymphocytes synthesize and release functional osteoprotegerin in vitro","year":2007,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Université Laval","funders":"","keywords":"Osteoprotegerin; RANKL; Internal medicine; Endocrinology; Immune system; Biology; Molecular biology; Receptor; Immunology; Chemistry; Activator (genetics); Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002896956,0.000122085,0.0001048327,0.00006565105,0.00008298136,0.00002252239,0.00005070211,0.0001147555,0.00001083481],"category_scores_gemma":[0.0001219833,0.0001285305,0.00002234595,0.0001472788,0.0001417401,0.00001817042,0.00004039431,0.00005755121,0.000005216425],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002474851,"about_ca_system_score_gemma":0.0001748185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002869495,"about_ca_topic_score_gemma":0.00004475906,"domain_scores_codex":[0.9991872,0.00005785241,0.0002036199,0.0002547846,0.0001224405,0.0001741543],"domain_scores_gemma":[0.9995356,0.0000153417,0.00006923932,0.000166414,0.00007027871,0.0001431501],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001783151,0.00002762389,0.02578625,0.00003178366,0.000006121601,0.000006005753,0.00002648585,0.000008139315,0.9725451,0.0002179829,0.0001731279,0.0009930785],"study_design_scores_gemma":[0.0005293633,0.00002816016,0.3207511,0.000009268939,0.000009809365,0.000002692156,0.00004041524,0.000005342256,0.6759588,0.0001611986,0.002374013,0.0001299382],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997832,0.001433877,0.00009255888,0.0000470007,0.00007311754,0.0001351807,0.00003985808,0.0000187391,0.0003276627],"genre_scores_gemma":[0.9977108,0.00002546422,0.0006512832,0.0009566401,0.0002385455,0.00002209389,0.0003091018,0.00001500737,0.00007111762],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2965864,"threshold_uncertainty_score":0.5241324,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006774790503118275,"score_gpt":0.2051733357809746,"score_spread":0.1983985452778564,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}