{"id":"W2035339932","doi":"10.1371/journal.pone.0094999","title":"Functionally Distinct Effects of the C-Terminal Regions of IKKε and TBK1 on Type I IFN Production","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ministry of Education, Culture, Sports, Science and Technology; McGill University","keywords":"IκB kinase; TANK-binding kinase 1; Kinase; Innate immune system; Cell biology; Phosphorylation; Biology; Transcription factor; Signal transduction; Biochemistry; NF-κB; Immune system; Genetics; Protein kinase A; MAP kinase kinase kinase; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002474706,0.0003663019,0.0002191075,0.0001377119,0.000117456,0.0002159171,0.0003224436,0.0002521358,0.001140349],"category_scores_gemma":[0.0002465603,0.0001590462,0.0003352907,0.0001256906,0.0003788222,0.0002462756,0.0001692974,0.000633585,0.0002349899],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003063981,"about_ca_system_score_gemma":0.0002066744,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004023479,"about_ca_topic_score_gemma":0.0003807868,"domain_scores_codex":[0.9997912,0.00004323568,0.00002831823,0.00004117952,0.0000325017,0.00006355125],"domain_scores_gemma":[0.999777,0.00005882633,0.00005768242,0.00002744312,0.00001374078,0.00006533626],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004888104,0.00003340771,0.0001171215,0.00002523729,0.000003734144,0.00002705405,0.000006975029,0.00006425603,0.9988932,0.00005121702,0.00000638912,0.00028265],"study_design_scores_gemma":[0.00003297684,0.0002841696,0.003182412,0.000005048537,0.00001911752,0.0001764952,0.00002268697,0.0006138813,0.9951862,0.00003904987,0.0004333199,0.000004656402],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984457,0.0005621001,0.0005435855,0.00002634534,0.00001619354,0.000006197334,0.0001177576,0.000006741059,0.0002754628],"genre_scores_gemma":[0.9978099,0.0002832905,0.001043439,0.00003093347,0.000004522847,0.00002041777,0.0003610584,0.00001037941,0.0004359385],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001140349,"threshold_uncertainty_score":0.003814876,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01832880959762673,"score_gpt":0.2044498814260803,"score_spread":0.1861210718284535,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}