{"id":"W2035339932","doi":"10.1371/journal.pone.0094999","title":"Functionally Distinct Effects of the C-Terminal Regions of IKKε and TBK1 on Type I IFN Production","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ministry of Education, Culture, Sports, Science and Technology; McGill University","keywords":"IκB kinase; TANK-binding kinase 1; Kinase; Innate immune system; Cell biology; Phosphorylation; Biology; Transcription factor; Signal transduction; Biochemistry; NF-κB; Immune system; Genetics; Protein kinase A; MAP kinase kinase kinase; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001093255,0.00006227227,0.0001421488,0.00003709083,0.00007258121,0.000001599129,0.00006803479,0.00006024279,0.00004570138],"category_scores_gemma":[0.0007012061,0.00004126174,0.0000300393,0.00005267353,0.0001854297,0.00001832613,0.00003356443,0.0001261945,0.00003285376],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007220743,"about_ca_system_score_gemma":0.00001780191,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001003097,"about_ca_topic_score_gemma":0.000005336818,"domain_scores_codex":[0.999457,0.0002162779,0.0001148756,0.000103616,0.00003062844,0.00007762144],"domain_scores_gemma":[0.9994363,0.0002097448,0.00008313037,0.0001915491,0.0000742644,0.00000501808],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007840475,0.0005601468,0.001567482,0.0001288432,0.0001534952,1.779774e-7,0.0001195814,2.001139e-7,0.9940904,0.001021675,0.0007460563,0.0008278693],"study_design_scores_gemma":[0.0003274002,0.0009809276,0.1072406,0.0002814924,0.00009296447,0.00001563457,0.00001522719,0.000001437952,0.8898818,0.00009390496,0.001021556,0.00004696438],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981498,0.0003220626,0.000009055166,0.0003419774,0.0003218124,0.0001405261,0.000002222409,0.00001018243,0.0007023672],"genre_scores_gemma":[0.9922658,0.00002284542,0.00001437832,0.00004210991,0.00002463408,0.000005700982,0.000005589131,0.000005278607,0.00761367],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1056732,"threshold_uncertainty_score":0.1682605,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01832880959762673,"score_gpt":0.2044498814260803,"score_spread":0.1861210718284535,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}