{"id":"W2035344693","doi":"10.1139/v06-015","title":"Synthesis of some new 1-aryl-4-formyl-3-(4-hydroxy-6-methyl-2-oxo-2<i>H</i>-pyran-3-yl)pyrazoles using the Vilsmeier–Haack reaction — Isolation of the key intermediate 1-aryl-3-(4-hydroxy-6-methyl-2-oxo-2<i>H</i>-pyran-3-yl)pyrazoles","year":2006,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chemistry; Dehydroacetic acid; Pyran; Moiety; Reagent; Aryl; Medicinal chemistry; Organic chemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001766213,0.0004654147,0.0003234251,0.0002157527,0.0002413961,0.0001578341,0.0005293511,0.0004320042,0.001439517],"category_scores_gemma":[0.0001795785,0.0002325021,0.0003043744,0.0002468694,0.0002351959,0.0003708067,0.0002876859,0.0006158187,0.0006835104],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000335582,"about_ca_system_score_gemma":0.0002976788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007621203,"about_ca_topic_score_gemma":0.001323594,"domain_scores_codex":[0.9998885,0.00001476361,0.00001122216,0.00002099669,0.0000199482,0.00004452632],"domain_scores_gemma":[0.9999195,0.000007703171,0.00002386963,0.000008252191,0.00001590084,0.00002477841],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001032446,0.0000733093,0.000187281,0.0003171799,0.0000141762,0.0005329194,0.0001493496,0.0003716231,0.9922714,0.0008661101,0.0003113455,0.004801977],"study_design_scores_gemma":[0.00006808933,0.001241142,0.002169183,0.0000189994,0.00002933223,0.000632684,0.00007333328,0.0009415321,0.9820043,0.0001769674,0.01261374,0.0000306404],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9573029,0.008756942,0.02101842,0.000342064,0.0002088409,0.0002702382,0.001132457,0.0004344095,0.01053373],"genre_scores_gemma":[0.980141,0.004306063,0.0101056,0.0001009158,0.00003697818,0.0001287191,0.0005085405,0.00002806335,0.004644205],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001439517,"threshold_uncertainty_score":0.004815638,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01018670110184684,"score_gpt":0.2116761216142388,"score_spread":0.201489420512392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}