{"id":"W2035376266","doi":"10.1371/journal.ppat.1003518","title":"The Salmonella Type III Effector SspH2 Specifically Exploits the NLR Co-chaperone Activity of SGT1 to Subvert Immunity","year":2013,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Plant-Microbe Interactions and Immunity","field":"Agricultural and Biological Sciences","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Canada's Michael Smith Genome Sciences Centre","funders":"Medical Research Council; National Health and Medical Research Council; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Alexander von Humboldt-Stiftung; University of British Columbia; National Institutes of Health; Michael Smith Health Research BC; Nationwide Children's Hospital","keywords":"Effector; Ubiquitin ligase; Biology; Chaperone (clinical); Cell biology; Ubiquitin; Innate immune system; F-box protein; NOD1; Cullin; Receptor; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001323487,0.0003604684,0.0002507145,0.00009639556,0.00009440885,0.0002593375,0.0001066727,0.0002445968,0.000713319],"category_scores_gemma":[0.0000568205,0.0001037419,0.0003119055,0.00008954407,0.0001514466,0.000149007,0.0002950195,0.0003408996,0.000414217],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002485356,"about_ca_system_score_gemma":0.0001471157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001601515,"about_ca_topic_score_gemma":0.0003040191,"domain_scores_codex":[0.9999094,0.00001550025,0.000008614689,0.00002058722,0.00002511046,0.00002079413],"domain_scores_gemma":[0.9999394,0.000006986685,0.00001919453,0.000009752692,0.00000793585,0.00001668296],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003805942,0.000007494723,0.000208973,0.00002347379,0.000003486796,0.00003252657,0.000003717921,0.00005819862,0.9988793,0.00003600497,0.00002403227,0.0006847717],"study_design_scores_gemma":[0.000006715433,0.0001332567,0.002199501,0.000001683623,0.000007255466,0.0002432862,0.000009713684,0.0007833,0.9948862,0.00001911561,0.001707435,0.000002498063],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902266,0.001018305,0.006803829,0.0001057219,0.00003813966,0.00002307884,0.0003146831,0.000172545,0.001297108],"genre_scores_gemma":[0.9945391,0.0003487042,0.002515147,0.00005599496,0.000009065692,0.000009258683,0.0005589724,0.00002136461,0.001942447],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000713319,"threshold_uncertainty_score":0.002386272,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03131843970968615,"score_gpt":0.229185099935391,"score_spread":0.1978666602257048,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}