{"id":"W2035392155","doi":"10.1038/labinvest.3700237","title":"Prolonged β-catenin stabilization and tcf-dependent transcriptional activation in hyperplastic cutaneous wounds","year":2005,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre; Hospital for Sick Children","funders":"Canada Research Chairs","keywords":"Wound healing; Beta-catenin; GSK-3; Mesenchymal stem cell; GSK3B; Biology; Catenin; Pathology; Cancer research; Kinase; Medicine; Immunology; Cell biology; Signal transduction; Wnt signaling pathway","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001903527,0.0001919209,0.0001972136,0.0004207005,0.0002393509,0.0003409846,0.0001486741,0.0002219708,0.003024296],"category_scores_gemma":[0.0001750215,0.0002191717,0.0002397641,0.0002360966,0.0002910136,0.0002718935,0.0002007603,0.0007672365,0.000346268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003474609,"about_ca_system_score_gemma":0.0001590593,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006539333,"about_ca_topic_score_gemma":0.0006297661,"domain_scores_codex":[0.999821,0.00004129125,0.00001606861,0.00003458645,0.00003572012,0.00005130973],"domain_scores_gemma":[0.9998546,0.00003377343,0.0000252877,0.00002818471,0.00001441518,0.00004372512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000264766,0.00003135393,0.0001161486,0.00001887286,0.000002549673,0.00009924429,0.00001153725,0.0000224812,0.9986028,0.0001169378,0.00002573939,0.0006876028],"study_design_scores_gemma":[0.00002002455,0.0002186684,0.005831161,0.000003179726,0.00001051285,0.0008847862,0.00004288028,0.0005136019,0.9915793,0.00006283038,0.0008307055,0.00000242918],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942562,0.002116665,0.001893022,0.00006927608,0.00002423415,0.00001958587,0.000162916,0.00004865677,0.001409449],"genre_scores_gemma":[0.9966582,0.0003331229,0.0005954675,0.00002654126,0.00001213329,0.00002571025,0.0001336101,0.00000922593,0.002206128],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003024296,"threshold_uncertainty_score":0.01011735,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008143481845614085,"score_gpt":0.2112825311907094,"score_spread":0.2031390493450953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}