{"id":"W2035444091","doi":"10.1006/excr.2001.5243","title":"Oxygen-Mediated Regulation of Gelatinase and Tissue Inhibitor of Metalloproteinases-1 Expression by Invasive Cells","year":2001,"lang":"en","type":"article","venue":"Experimental Cell Research","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"","keywords":"Matrix metalloproteinase; Biology; Gelatinase; Zymography; Trophoblast; Matrigel; Secretion; Cell culture; Extracellular matrix; Gentamicin protection assay; Western blot; Cancer cell; Cell migration; Tissue inhibitor of metalloproteinase; Molecular biology; Cancer research; Endocrinology; Cell biology; Angiogenesis; Placenta; Cancer; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003466599,0.0001258337,0.0001568252,0.00008452777,0.00007719606,0.00001080155,0.0001298048,0.0001518961,0.0001596677],"category_scores_gemma":[0.00005715164,0.0001183732,0.00004160298,0.0001388607,0.0001660316,0.000012851,0.0002429888,0.000105524,0.000008715935],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001915341,"about_ca_system_score_gemma":0.00006033198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008215456,"about_ca_topic_score_gemma":0.000002252393,"domain_scores_codex":[0.9985946,0.0001916553,0.0002543316,0.0003215282,0.0003982188,0.0002396731],"domain_scores_gemma":[0.999341,0.00003495885,0.0001006645,0.0002716607,0.0001324376,0.0001192474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002649777,0.0002663651,0.00003167385,0.00004236283,0.000008364016,0.000003823402,0.0001178419,0.000001384511,0.9962971,0.00001075373,0.002832378,0.0001229423],"study_design_scores_gemma":[0.0007004132,0.001327542,0.0000154264,0.00004212822,0.000002628513,0.000002679205,0.000441702,0.00001281904,0.9942647,0.00003590056,0.003042265,0.000111792],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926333,0.005294585,0.00007178493,0.00001304525,0.00003805696,0.0005443618,0.0000316952,0.000004817486,0.001368336],"genre_scores_gemma":[0.9976691,0.0002906304,0.0005972238,0.00001045936,0.00007159798,0.00005992426,0.0001526506,0.00002117178,0.001127216],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005035809,"threshold_uncertainty_score":0.4827117,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02061840711426151,"score_gpt":0.3046647570444742,"score_spread":0.2840463499302127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}