{"id":"W2035444091","doi":"10.1006/excr.2001.5243","title":"Oxygen-Mediated Regulation of Gelatinase and Tissue Inhibitor of Metalloproteinases-1 Expression by Invasive Cells","year":2001,"lang":"en","type":"article","venue":"Experimental Cell Research","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"","keywords":"Matrix metalloproteinase; Biology; Gelatinase; Zymography; Trophoblast; Matrigel; Secretion; Cell culture; Extracellular matrix; Gentamicin protection assay; Western blot; Cancer cell; Cell migration; Tissue inhibitor of metalloproteinase; Molecular biology; Cancer research; Endocrinology; Cell biology; Angiogenesis; Placenta; Cancer; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001971632,0.0003734692,0.0002755517,0.0002625971,0.0002572599,0.0004853739,0.0002465606,0.0002986023,0.001455689],"category_scores_gemma":[0.0002263234,0.000190793,0.0003566042,0.000171556,0.0002627549,0.0004613283,0.0002598049,0.0005554355,0.0002328158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003098347,"about_ca_system_score_gemma":0.0001395305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007872131,"about_ca_topic_score_gemma":0.001047456,"domain_scores_codex":[0.9997558,0.0000368608,0.00001425896,0.00003240257,0.00005013356,0.0001104143],"domain_scores_gemma":[0.9997955,0.00007352621,0.00003167448,0.00003155112,0.00002831484,0.00003939397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002533581,0.00003329022,0.0001459358,0.00002109634,0.00000204664,0.00005319341,0.00004326054,0.00001386388,0.998415,0.0001763619,0.00004195419,0.0008006327],"study_design_scores_gemma":[0.00003070545,0.0002515309,0.01196728,0.00000472111,0.00001305787,0.000183438,0.0001214552,0.000729887,0.9846441,0.0001431397,0.001905397,0.000005314772],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925787,0.002486205,0.002655651,0.0001364006,0.00004940709,0.00003354455,0.000195563,0.00004374091,0.001820708],"genre_scores_gemma":[0.992698,0.001157357,0.001564019,0.00006568876,0.00003171207,0.00006458998,0.0005788138,0.0000162599,0.003823499],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001455689,"threshold_uncertainty_score":0.004869759,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02061840711426151,"score_gpt":0.3046647570444742,"score_spread":0.2840463499302127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}