{"id":"W2035457643","doi":"10.1021/tx000123x","title":"In Vitro Effect of Arsenical Compounds on Glutathione-Related Enzymes","year":2001,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Arsenic contamination and mitigation","field":"Environmental Science","cited_by":124,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"School of Medicine, New York University; York University; National Institute of Environmental Health Sciences; Electric Power Research Institute; U.S. Environmental Protection Agency","keywords":"Glutathione; Sodium arsenite; Arsenite; Glutathione reductase; Chemistry; Arsenic; Glutathione peroxidase; Biochemistry; Arsenic toxicity; GPX1; Enzyme; Arsenate; GPX3; GPX4","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001464142,0.00008087559,0.0001989712,0.0001439211,0.00002499067,0.000004334792,0.000205559,0.0002003927,0.0009395632],"category_scores_gemma":[0.0008728947,0.0000721825,0.00003824431,0.0005875615,0.0005582509,0.0000665648,0.0001714666,0.0005649558,0.0002340509],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004486209,"about_ca_system_score_gemma":0.00001943517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006441056,"about_ca_topic_score_gemma":0.00004639348,"domain_scores_codex":[0.9982129,0.0004702642,0.0002899548,0.0002762849,0.0003751417,0.0003754762],"domain_scores_gemma":[0.9981994,0.001505572,0.00003431366,0.0001557068,0.000009238667,0.0000957519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004541034,0.0002359488,0.003830152,0.000006156478,0.000002254428,0.0000679213,0.000133592,0.0000247361,0.979344,0.000833241,0.0006830319,0.01438483],"study_design_scores_gemma":[0.001763244,0.0004112075,0.01045826,0.0000203749,0.000001374819,0.000018283,0.00003365732,0.002353999,0.9800097,0.001999778,0.002841742,0.00008839115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9757877,0.00001716103,0.000003218226,0.002266614,0.00004611611,0.0002441937,9.64134e-7,0.000009209753,0.02162483],"genre_scores_gemma":[0.9993487,0.00001911761,0.00004368383,0.0001076847,0.00001222913,0.00004202392,0.000007296441,0.000006423358,0.0004128371],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02356101,"threshold_uncertainty_score":0.9999737,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03164618450453267,"score_gpt":0.3667793416382057,"score_spread":0.3351331571336731,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}