{"id":"W2035471462","doi":"10.1016/j.jceh.2014.02.004","title":"Pathogenesis of Hepatic Encephalopathy and Brain Edema in Acute Liver Failure","year":2014,"lang":"en","type":"review","venue":"Journal of Clinical and Experimental Hepatology","topic":"Liver Disease and Transplantation","field":"Medicine","cited_by":137,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Hôpital Saint-Luc","funders":"","keywords":"Medicine; Hepatic encephalopathy; Microglia; Pathogenesis; Neurotoxicity; Cerebral edema; Edema; Brain edema; Minocycline; Encephalopathy; Pharmacology; Inflammation; Pathology; Immunology; Internal medicine; Cirrhosis; Toxicity; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005901727,0.0009522947,0.002120067,0.002410277,0.0003070292,0.001392372,0.001113582,0.001324071,0.001614139],"category_scores_gemma":[0.0008093494,0.0003062171,0.000527448,0.002245903,0.0007570426,0.001593314,0.0008488173,0.001509247,0.0006526471],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005388583,"about_ca_system_score_gemma":0.00130185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00143436,"about_ca_topic_score_gemma":0.002240191,"domain_scores_codex":[0.9998122,0.00003496328,0.0000464416,0.00002990231,0.00005750983,0.00001892271],"domain_scores_gemma":[0.9996507,0.0001584072,0.00008448293,0.000007109079,0.0000734965,0.00002569539],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000151446,0.0001349557,0.001135178,0.03248874,0.000223929,0.00106896,0.0001083739,0.00045158,0.001149044,0.003511518,0.02219588,0.9373806],"study_design_scores_gemma":[0.0001078103,0.0002717432,0.007114604,0.01894417,0.001024722,0.01477533,0.0004597219,0.0004930494,0.0008529593,0.008291828,0.9475474,0.0001167459],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007493611,0.999491,0.00004136511,0.0001357828,0.00006790696,0.000001801547,0.000005164018,0.000001583403,0.0001804625],"genre_scores_gemma":[0.0006396096,0.9988911,0.00008047529,0.00008236265,0.0001988308,0.000002184205,0.000008707442,2.627049e-7,0.00009658766],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002410277,"threshold_uncertainty_score":0.005399883,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05011450008106921,"score_gpt":0.4122716298452406,"score_spread":0.3621571297641714,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}